Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 13/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12186444 | 0.86 | ADRB2 (0.50) | ADRB2HIF1AALDH1A1TDP1KDM4E | |
| SCHEMBL19329750 | 0.86 | ADRB2 (0.67) | ADRB2HIF1AALDH1A1TDP1KDM4E | |
| SCHEMBL12186437 | 0.86 | ADRB2 (0.50) | ADRB2HIF1AALDH1A1TDP1KDM4E | |
| SCHEMBL12186453 | 0.84 | ADRB3 (0.49) | ADRB2HIF1AALDH1A1TDP1KDM4E | |
| SCHEMBL12186441 | 0.84 | ADRB3 (0.49) | ADRB2HIF1AALDH1A1TDP1KDM4E | |
| SCHEMBL12186451 | 0.84 | ADRB2 (0.49) | ADRB2HIF1AALDH1A1TDP1KDM4E | |
| SCHEMBL12186435 | 0.84 | ADRB2 (0.49) | ADRB2HIF1AALDH1A1TDP1KDM4E | |
| SCHEMBL12186577 | 0.84 | KDM4E (0.57) | ADRB2KDM4EADRB1ADRB3LMNA | |
| SCHEMBL12186584 | 0.84 | KDM4E (0.57) | ADRB2KDM4EADRB1ADRB3LMNA | |
| Deterenol SCHEMBL31419987 | 0.83 | ADRB2 (0.67) | ADRB2HIF1AALDH1A1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306162-A1 | Treatment of Inflammatory Disorders and Pain | SOSEI R&D LTD. (GB) | 2008-12-11 | — | — | US | claimed |
| US-20080306162-A1 | Treatment of Inflammatory Disorders and Pain | SOSEI R&D LTD. (GB) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306162-A1 | Treatment of Inflammatory Disorders and Pain | HRH3, OPRL1, HRH2 | ADRB2 131/4885HIF1A 1202/4885ALDH1A1 3960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.