Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4878146 | 1.00 | HCAR2 (0.47) | HCAR2ALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL4878144 | 1.00 | HCAR2 (0.47) | HCAR2ALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL16160014 | 0.86 | MAPT (0.48) | HCAR2ALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL5462461 | 0.80 | MAPT (0.46) | HCAR2ALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL5462463 | 0.80 | MAPT (0.46) | HCAR2ALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL8182843 | 0.77 | AKR1C3 (0.52) | HCAR2ALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL1930557 | 0.77 | AKR1C3 (0.52) | HCAR2ALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL8303646 | 0.76 | HCAR2 (0.55) | HCAR2ALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL11539420 | 0.76 | HCAR2 (0.55) | HCAR2ALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL8303644 | 0.76 | HCAR2 (0.55) | HCAR2ALDH1A1MAPTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242876-A1 | Process For the Manufacture of Substituted Propionic Acids | PHOENIX CHEMICALS LTD. (GB) | 2008-10-02 | — | — | US | disclosed |
| EP-1838654-A1 | PROCESS FOR THE MANUFACTURE OF SUBSTITUTED PROPIONIC ACIDS | Phoenix Chemicals Limited (GB) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006075177-A1 | PROCESS FOR THE MANUFACTURE OF SUBSTITUTED PROPIONIC ACIDS | PHOENIX CHEMICALS LTD. (GB) | 2006-07-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242876-A1 | Process For the Manufacture of Substituted Propionic Acids | AS3MT, PPA1, AGPS | HCAR2 1009/4885ALDH1A1 14/4885MAPT 3886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.