Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GCK | P35557 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303644 | 1.00 | HCAR2 (0.55) | HCAR2KMT2AMAPTLMNANPSR1 | |
| SCHEMBL11539420 | 0.83 | HCAR2 (0.55) | HCAR2KMT2AMAPTLMNANPSR1 | |
| SCHEMBL8436581 | 0.80 | HCAR2 (0.52) | HCAR2KMT2AMAPTLMNANPSR1 | |
| SCHEMBL9709967 | 0.80 | HCAR2 (0.52) | HCAR2KMT2AMAPTLMNANPSR1 | |
| SCHEMBL8182843 | 0.80 | AKR1C3 (0.52) | HCAR2KMT2AMAPTLMNANPSR1 | |
| SCHEMBL8436579 | 0.80 | HCAR2 (0.52) | HCAR2KMT2AMAPTLMNANPSR1 | |
| SCHEMBL1930557 | 0.80 | AKR1C3 (0.52) | HCAR2KMT2AMAPTLMNANPSR1 | |
| SCHEMBL9709969 | 0.80 | HCAR2 (0.52) | HCAR2KMT2AMAPTLMNANPSR1 | |
| SCHEMBL9709963 | 0.80 | HCAR2 (0.52) | HCAR2KMT2AMAPTLMNANPSR1 | |
| SCHEMBL11074306 | 0.79 | HCAR2 (0.50) | HCAR2KMT2AMAPTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581250-B1 | Process for biotechnical preparation of L-thienylalanines in enantiomere pure form from 2-hydroxy-3-thienyl-acrylic acids and their use | HOECHST AG (DE) | 1999-03-03 | — | — | EP | claimed |
| US-5480786-A | Process for the biotechnological preparation of l-thienylalanines in enantiomerically pure form from 2-hydroxy-3-thienylacrylic acids, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-02 | — | — | US | claimed |
| JP-6165687-A | — | — | None | — | — | JP | disclosed |
| EP-3339300-B1 | METHOD FOR PREPARING THIENYL ALANINE HAVING OPTICAL ACTIVITY | AMINOLOGICS CO LTD (KR) | 2020-08-12 | — | — | EP | disclosed |
| US-10562879-B2 | Method for preparing thienyl alanine having optical activity | AMINOLOGICS CO., LTD. (KR) | 2020-02-18 | — | — | US | disclosed |
| US-20180290996-A1 | METHOD FOR PREPARING THIENYL ALANINE HAVING OPTICAL ACTIVITY | AMINOLOGICS CO., LTD. (KR) | 2018-10-11 | — | — | US | disclosed |
| EP-3339300-A1 | METHOD FOR PREPARING THIENYL ALANINE HAVING OPTICAL ACTIVITY | Aminologics Co., Ltd. (KR) | 2018-06-27 | — | — | EP | disclosed |
| EP-0581250-B1 | Process for biotechnical preparation of L-thienylalanines in enantiomere pure form from 2-hydroxy-3-thienyl-acrylic acids and their use | HOECHST AG (DE) | 1999-03-03 | — | — | EP | disclosed |
| EP-0581250-B1 | Process for biotechnical preparation of L-thienylalanines in enantiomere pure form from 2-hydroxy-3-thienyl-acrylic acids and their use | HOECHST AG (DE) | 1999-03-03 | — | — | EP | disclosed |
| US-5780640-A | Process for the biotechnological preparation of L-thienylalanines in enantiomerically pure form from 2-hydroxy-3-thienylacrylic acids and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |
| US-5780640-A | Process for the biotechnological preparation of L-thienylalanines in enantiomerically pure form from 2-hydroxy-3-thienylacrylic acids and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |
| US-5688672-A | Process for the biotechnological preparation of L-thienylalanines in enantiomerically pure form from 2-hydroxy-3-thienylacrylic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-18 | — | — | US | disclosed |
| US-5688672-A | Process for the biotechnological preparation of L-thienylalanines in enantiomerically pure form from 2-hydroxy-3-thienylacrylic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-18 | — | — | US | disclosed |
| US-5480786-A | Process for the biotechnological preparation of l-thienylalanines in enantiomerically pure form from 2-hydroxy-3-thienylacrylic acids, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-02 | — | — | US | disclosed |
| US-5480786-A | Process for the biotechnological preparation of l-thienylalanines in enantiomerically pure form from 2-hydroxy-3-thienylacrylic acids, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-02 | — | — | US | disclosed |
| US-5480786-A | Process for the biotechnological preparation of l-thienylalanines in enantiomerically pure form from 2-hydroxy-3-thienylacrylic acids, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-02 | — | — | US | disclosed |
| JP-H06165687-A | BIOTECHNOLOGICAL PREPARATION OF L-THIENYLALANINE IN ENANTIOMERICALLY PURE FORM FROM 2-HYDROXY-3-THIENYLACRYLIC ACID AND ITS USE | HOECHST AG | 1994-06-14 | — | — | JP | disclosed |
| EP-0581250-A2 | Process for biotechnical preparation of L-thienylalanines in enantiomere pure form from 2-hydroxy-3-thienyl-acrylic acids and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-02 | — | — | EP | disclosed |
| EP-0581250-A2 | Process for biotechnical preparation of L-thienylalanines in enantiomere pure form from 2-hydroxy-3-thienyl-acrylic acids and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-02 | — | — | EP | disclosed |
| EP-0581250-A2 | Process for biotechnical preparation of L-thienylalanines in enantiomere pure form from 2-hydroxy-3-thienyl-acrylic acids and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10562879-B2 | Method for preparing thienyl alanine having optical activity | ALAD, AADAT, THOP1 | HCAR2 1690/4885KMT2A 3903/4885MAPT 670/4885 |
| US-20180290996-A1 | METHOD FOR PREPARING THIENYL ALANINE HAVING OPTICAL ACTIVITY | ALAD, AADAT, THOP1 | HCAR2 1690/4885KMT2A 3903/4885MAPT 670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.