Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 5/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169053 | 0.90 | SLC22A12 (0.46) | KCNN4SLC22A12KIF11LMNAGAA | |
| SCHEMBL29466225 | 0.90 | SLC22A12 (0.46) | KCNN4SLC22A12KIF11LMNAGAA | |
| Hydrochloric Acid SCHEMBL28030629 | 0.87 | ALDH1A1 (0.48) | KCNN4SLC22A12KIF11LMNAGAA | |
| Bromide SCHEMBL27721879 | 0.87 | SLC22A12 (0.44) | KCNN4SLC22A12KIF11LMNAGAA | |
| Ammonia Solution, Strong SCHEMBL2163470 | 0.87 | SLC22A12 (0.44) | KCNN4SLC22A12KIF11LMNAGAA | |
| SCHEMBL5486293 | 0.85 | GAA (0.45) | KIF11LMNAGAAALDH1A1POLB | |
| Formaldehyde SCHEMBL28254541 | 0.83 | SLC22A12 (0.46) | KCNN4SLC22A12LMNAGAAALDH1A1 | |
| Methylamine SCHEMBL27811451 | 0.83 | ALDH1A1 (0.45) | KCNN4SLC22A12KIF11ALDH1A1POLB | |
| Isothiocyanate SCHEMBL27973963 | 0.77 | SLC22A12 (0.39) | KCNN4SLC22A12KIF11ALDH1A1POLB | |
| SCHEMBL27687338 | 0.77 | SLC22A12 (0.50) | KCNN4SLC22A12KIF11LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105985319-B | Aryl phthalazine compound and its preparation method and application | 复旦大学 | 2019-02-26 | — | — | CN | disclosed |
| CN-106281356-A | Fluorinated liquid crystal containing difluoro-methoxy bridged bond and diyl and combinations thereof thing | 福建省邵武市永晶化工有限公司 | 2017-01-04 | — | — | CN | disclosed |
| CN-106244168-A | Fluorinated liquid crystal containing difluoro-methoxy bridged bond and polyfluoro xenyl and combinations thereof thing | 福建永晶科技有限公司 | 2016-12-21 | — | — | CN | disclosed |
| US-9493478-B2 | Fused ring compound containing furan or salt thereof and pharmaceutical composition comprising same | YUHAN CORPORATION (KR) | 2016-11-15 | — | — | US | disclosed |
| CN-104449762-B | Fluorine-containing liquid crystal containing difluoromethoxy bridge bond and composition thereof | 福建省邵武市永晶化工有限公司 | 2016-09-14 | — | — | CN | disclosed |
| US-20150191478-A1 | FUSED RING COMPOUND CONTAINING FURAN OR SALT THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | YUHAN CORPORATION (KR) | 2015-07-09 | — | — | US | disclosed |
| EP-2876109-A1 | FUSED RING COMPOUND CONTAINING FURAN OR SALT THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Yuhan Corporation (KR) | 2015-05-27 | — | — | EP | disclosed |
| US-20080076771-A1 | Thrombopoietin Receptor Agonists | REITER LAWRENCE A | 2008-03-27 | — | — | US | disclosed |
| EP-1794156-A2 | TROMBOPOIETIN RECEPTOR AGONISTS | Pfizer Products Incorporated (US) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006033005-A2 | THROMBOPOIETIN RECEPTOR AGONISTS | PFIZER PRODUCTS INC. (US) | 2006-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191478-A1 | FUSED RING COMPOUND CONTAINING FURAN OR SALT THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | PIK3CD, PIK3CA, MTOR | KCNN4 920/4885SLC22A12 2121/4885KIF11 3806/4885 |
| US-20080076771-A1 | Thrombopoietin Receptor Agonists | MPL, THPO, TBXA2R | KCNN4 4029/4885SLC22A12 3578/4885KIF11 4100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.