Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4902008 | 1.00 | ADRA2A (0.40) | ADRA2AADRA2BADRA2CSLC22A12CDC7 | |
| SCHEMBL4809329 | 0.87 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CSLC22A12CDC7 | |
| SCHEMBL8216819 | 0.87 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CSLC22A12CDC7 | |
| SCHEMBL4809335 | 0.87 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CSLC22A12CDC7 | |
| SCHEMBL4873114 | 0.82 | SLC22A12 (0.41) | ADRA2AADRA2BADRA2CSLC22A12CDC7 | |
| SCHEMBL4873110 | 0.82 | SLC22A12 (0.41) | ADRA2AADRA2BADRA2CSLC22A12CDC7 | |
| SCHEMBL4810720 | 0.76 | CDC7 (0.40) | SLC22A12CDC7CDK2PARP1RAPGEF4 | |
| SCHEMBL8223459 | 0.76 | CDC7 (0.40) | SLC22A12CDC7CDK2PARP1RAPGEF4 | |
| SCHEMBL4810714 | 0.76 | CDC7 (0.40) | SLC22A12CDC7CDK2PARP1RAPGEF4 | |
| SCHEMBL4809383 | 0.76 | SLC22A12 (0.37) | SLC22A12CDC7CDK2PARP1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080090834-A1 | SELECTIVE AZOLE PDE10A INHIBITOR COMPOUNDS | PFIZER INC | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090834-A1 | SELECTIVE AZOLE PDE10A INHIBITOR COMPOUNDS | PDE5A, PDE3B, PDE12 | ADRA2A 781/4885ADRA2B 664/4885ADRA2C 476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.