Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GALK1 | P51570 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6199094 | 0.80 | GAA (0.40) | GAAKDM4EPOLBALDH1A1ABL1 | |
| SCHEMBL28165678 | 0.80 | GAA (0.40) | GAAKDM4EPOLBALDH1A1ABL1 | |
| SCHEMBL4874700 | 0.80 | KDM4E (0.41) | GAAHPGDKDM4EPOLBALDH1A1 | |
| SCHEMBL11456734 | 0.80 | KDM4E (0.49) | GAAHPGDKDM4EPOLBALDH1A1 | |
| SCHEMBL233448 | 0.76 | KDM4E (0.36) | GAAKDM4EALDH1A1HSD17B10TAS1R3 | |
| SCHEMBL4831667 | 0.74 | GALK1 (0.49) | GAAGALK1HPGDKDM4EPOLB | |
| SCHEMBL3327287 | 0.73 | NR4A2 (0.51) | GAAHPGDKDM4EPOLBALDH1A1 | |
| SCHEMBL18393285 | 0.73 | GALK1 (0.51) | GAAGALK1HPGDKDM4EPOLB | |
| SCHEMBL5465624 | 0.73 | ABL1 (0.42) | GAAKDM4EPOLBALDH1A1ABL1 | |
| SCHEMBL1712644 | 0.73 | ABL1 (0.42) | GAAHPGDKDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080300288-A1 | Alkenyldiarylmethanes, Fused Analogs And Syntheses Thereof | PURDUE RESEARCH FOUNDATION (US) | 2008-12-04 | — | — | US | disclosed |
| WO-2007005531-A2 | ALKENYLDIARYLMETHANES, FUSED ANALOGS AND SYNTHESES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300288-A1 | Alkenyldiarylmethanes, Fused Analogs And Syntheses Thereof | POLRMT, PNP, TYMS | GAA 232/4885GALK1 843/4885HPGD 626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.