Phenanthrene

Phenanthrene

SCHEMBL4879064

c1ccc2c(c1)-c1ccccc1-2.c1ccc2c(c1)ccc1ccccc12

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.80
HSD17B10 Q99714 6/20 0.80
TSHR P16473 5/20 0.80
CYP2A6 P11509 3/20 0.80
TDP1 Q9NUW8 1/20 0.80
HPRT1 P00492 3/20 0.71
HIF1A Q16665 2/20 0.63
CYP1B1 Q16678 1/20 0.63
DNMT1 P26358 1/20 0.56
PAX8 Q06710 1/20 0.55
HPGD P15428 3/20 0.54
MAPK1 P28482 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
CASP1 P29466 1/20 0.54
ATM Q13315 1/20 0.50
CYP3A4 P08684 2/20 0.48
CYP1A2 P05177 3/20 0.48
PTPN22 Q9Y2R2 1/20 0.48
THRB P10828 1/20 0.48
KEAP1 Q14145 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenanthrene SCHEMBL29358486 0.89 CYP2A6 (1.00) ALDH1A1HSD17B10TSHRCYP2A6TDP1
Phenanthrene SCHEMBL8873977 0.89 CYP2A6 (1.00) ALDH1A1HSD17B10TSHRCYP2A6TDP1
Phenanthrene SCHEMBL29477074 0.89 CYP2A6 (1.00) ALDH1A1HSD17B10TSHRCYP2A6TDP1
Phenanthrene SCHEMBL30932938 0.89 CYP2A6 (1.00) ALDH1A1HSD17B10TSHRCYP2A6TDP1
Phenanthrene SCHEMBL7643 0.89 CYP2A6 (1.00) ALDH1A1HSD17B10TSHRCYP2A6TDP1
Phenanthrene SCHEMBL27458043 0.89 CYP2A6 (1.00) ALDH1A1HSD17B10TSHRCYP2A6TDP1
Phenanthrene SCHEMBL1330750 0.89 CYP2A6 (1.00) ALDH1A1HSD17B10TSHRCYP2A6TDP1
SCHEMBL30103588 0.89 HPRT1 (0.74) ALDH1A1HSD17B10TSHRCYP2A6TDP1
Phenanthrene SCHEMBL29177918 0.88 ALDH1A1 (0.71) ALDH1A1HSD17B10TSHRCYP2A6TDP1
SCHEMBL25402118 0.87 HPRT1 (0.70) ALDH1A1HSD17B10TSHRCYP2A6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US disclosed