Triaziquone

Triaziquone

SCHEMBL4879123

CCO[PH](=O)O.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.36
STAT3 P40763 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
DNMT1 P26358 1/20 0.34
NSD2 O96028 1/20 0.31
TTR P02766 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL4407749 0.99 TP53 (0.35) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL5606305 0.82 HTT (0.42) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL11350903 0.82 HTT (0.42) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL6387848 0.81 MAPT (0.41) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL21358774 0.81 MAPT (0.43) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL451592 0.80 MAPT (0.40) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL21409933 0.80 DNMT1 (0.39) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL33439 0.79 HTT (0.42) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL2063810 0.79 MAPT (0.44) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL8303 0.79 DNMT1 (0.48) TP53MAPTSTAT3HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240167986-A1 METHODS AND COMPOSITIONS FOR ANALYTE QUANTIFICATION MATTERWORKS INC 2024-05-23 US disclosed
US-11754536-B2 Methods and compositions for analyte quantification MATTERWORKS INC (US) 2023-09-12 US disclosed
US-20230170049-A1 METHODS AND COMPOSITIONS FOR ANALYTE QUANTIFICATION MATTERWORKS INC 2023-06-01 US disclosed
US-20230137741-A1 METHODS AND COMPOSITIONS FOR ANALYTE QUANTIFICATION MATTERWORKS INC 2023-05-04 US disclosed
US-20230133615-A1 METHODS AND COMPOSITIONS FOR ANALYTE QUANTIFICATION MATTERWORKS INC 2023-05-04 US disclosed
WO-2023077166-A1 METHODS AND COMPOSITIONS FOR ANALYTE QUANTIFICATION MATTERWORKS INC (US) 2023-05-04 WO disclosed
CN-114556032-A Microbial compositions for preventing or reducing growth of fungal pathogens on plants 博思特生物群落公司 2022-05-27 CN disclosed
US-20080280763-A1 Method and composition for improving turfgrass TESSENDERLO KERLEY INC. 2008-11-13 US disclosed
US-5378708-A Agricultural pesticides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-01-03 US disclosed
EP-0577712-A1 FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-01-12 EP disclosed
EP-0356354-B1 Solid silicone compositions having an agricultural biological activity RHONE POULENC AGROCHIMIE (FR) 1993-10-27 EP disclosed
WO-1992016515-A1 FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-10-01 WO disclosed
WO-1992008704-A1 INSECTICIDAL, ACARICIDAL AND FUNGICIDAL AMINOPYRIMIDINES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-05-29 WO disclosed
EP-0449748-A1 Solid silicone compositions having an agricultural biological activity RHONE-POULENC AGROCHIMIE (FR) 1991-10-02 EP disclosed
EP-0356354-A1 Solid silicone compositions having an agricultural biological activity RHONE-POULENC AGROCHIMIE (FR) 1990-02-28 EP disclosed