Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | CCR6 | P51684 | 3/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779780 | 0.91 | CHRM2 (0.34) | KCNH2NPY2RCHRM2CHRM1LMNA | |
| SCHEMBL4778055 | 0.86 | CHRM2 (0.37) | KCNH2CHRM2CHRM1LMNASLC6A3 | |
| SCHEMBL4727024 | 0.85 | CHRM2 (0.33) | KCNH2CHRM2CHRM1LMNASLC6A3 | |
| SCHEMBL4780964 | 0.83 | HRH1 (0.34) | KCNH2CHRM2CHRM1LMNASLC6A3 | |
| SCHEMBL4727438 | 0.81 | CHRNA7 (0.38) | KCNH2NPY2RCHRM2CHRM1LMNA | |
| SCHEMBL4727311 | 0.79 | KCNH2 (0.39) | KCNH2CHRM2CHRM1LMNASLC6A3 | |
| SCHEMBL4743392 | 0.79 | LMNA (0.35) | KCNH2NPY2RCHRM2CHRM1LMNA | |
| SCHEMBL4743395 | 0.79 | LMNA (0.35) | KCNH2NPY2RCHRM2CHRM1LMNA | |
| SCHEMBL4801959 | 0.79 | LMNA (0.35) | KCNH2NPY2RCHRM2CHRM1LMNA | |
| SCHEMBL4801950 | 0.79 | LMNA (0.35) | KCNH2NPY2RCHRM2CHRM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008023157-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS M3-RECEPTOR MODULATORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |