Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179269 | 0.79 | CYP19A1 (0.46) | CYP19A1CYP3A4HSP90AA1CYP2D6SMN1; SMN2 | |
| SCHEMBL27886405 | 0.76 | CYP19A1 (0.47) | CYP19A1CYP3A4HSP90AA1CYP2D6KIF11 | |
| SCHEMBL31691964 | 0.76 | CYP19A1 (0.43) | CYP19A1CYP3A4HSP90AA1CYP2D6KIF11 | |
| SCHEMBL85669 | 0.76 | CYP19A1 (0.43) | CYP19A1CYP3A4HSP90AA1CYP2D6KIF11 | |
| SCHEMBL16454356 | 0.76 | CYP19A1 (0.43) | CYP19A1CYP3A4HSP90AA1CYP2D6KIF11 | |
| SCHEMBL16091462 | 0.76 | CYP19A1 (0.52) | CYP19A1CYP3A4HSP90AA1CYP2D6SMN1; SMN2 | |
| SCHEMBL16454702 | 0.76 | CYP19A1 (0.43) | CYP19A1CYP3A4HSP90AA1CYP2D6KIF11 | |
| SCHEMBL11713071 | 0.73 | CYP19A1 (0.36) | CYP19A1CYP3A4 | |
| SCHEMBL23842473 | 0.72 | CYP19A1 (0.41) | CYP19A1CYP3A4HSP90AA1CYP2D6 | |
| SCHEMBL16677128 | 0.72 | CYP19A1 (0.41) | CYP19A1CYP3A4HSP90AA1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015353-A1 | PROCESS FOR PRODUCTION OF 4-ACETYLPYRIMIDINES AND CRYSTALS THEREOF | AJINOMOTO CO., INC. (JP) | 2008-01-17 | — | — | US | disclosed |
| EP-1849761-A1 | PROCESS FOR PRODUCTION OF 4-ACETYLPYRIMIDINES AND CRYSTALS THEREOF | Ajinomoto Co., Inc. (JP) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015353-A1 | PROCESS FOR PRODUCTION OF 4-ACETYLPYRIMIDINES AND CRYSTALS THEREOF | DPYD, UMPS, PNPO | CYP19A1 2131/4885CYP3A4 12/4885HSP90AA1 4710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.