Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3605494 | 1.00 | BCHE (1.00) | BCHEACHE | |
| SCHEMBL3609657 | 1.00 | BCHE (1.00) | BCHEACHE | |
| SCHEMBL3589030 | 1.00 | BCHE (1.00) | BCHEACHE | |
| SCHEMBL3589499 | 1.00 | BCHE (1.00) | BCHEACHE | |
| SCHEMBL3598000 | 1.00 | BCHE (1.00) | BCHEACHE | |
| SCHEMBL3599570 | 1.00 | BCHE (1.00) | BCHEACHE | |
| Bromide SCHEMBL3591238 | 0.97 | BCHE (1.00) | BCHEACHE | |
| Iodide SCHEMBL5321839 | 0.97 | BCHE (0.94) | BCHEACHE | |
| Bromide SCHEMBL6354341 | 0.97 | BCHE (1.00) | BCHEACHE | |
| Bromide SCHEMBL9764843 | 0.97 | BCHE (1.00) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287490-A1 | Bis-pyridino containing compounds for the use in the treatment of CNS pathologies | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2008-11-20 | — | — | US | claimed |
| US-20050261334-A1 | Bis-pyridino containing compounds for the use in the treatment of CNS pathologies | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2005-11-24 | — | — | US | claimed |
| US-20080287490-A1 | Bis-pyridino containing compounds for the use in the treatment of CNS pathologies | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2008-11-20 | — | — | US | disclosed |
| US-20050261334-A1 | Bis-pyridino containing compounds for the use in the treatment of CNS pathologies | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261334-A1 | Bis-pyridino containing compounds for the use in the treatment of CNS pathologies | SLC18A3, SLC18A2, CHRNB2 | BCHE 58/4885ACHE 43/4885 |
| US-20080287490-A1 | Bis-pyridino containing compounds for the use in the treatment of CNS pathologies | SLC18A3, SLC18A2, CHRNB2 | BCHE 58/4885ACHE 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.