Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | P2RY12 | Q9H244 | 14/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3586010 | 0.85 | ALDH1A1 (0.71) | ALDH1A1P2RY12ACACBKDM4ENPSR1 | |
| SCHEMBL4005897 | 0.81 | ALDH1A1 (0.72) | ALDH1A1P2RY12KDM4ENPSR1 | |
| SCHEMBL29258456 | 0.78 | ALDH1A1 (0.69) | ALDH1A1P2RY12KDM4ENPSR1 | |
| SCHEMBL30999847 | 0.78 | ALDH1A1 (0.69) | ALDH1A1P2RY12KDM4ENPSR1 | |
| SCHEMBL4875331 | 0.76 | P2RY12 (0.56) | ALDH1A1P2RY12KDM4E | |
| SCHEMBL3599232 | 0.75 | ALDH1A1 (0.74) | ALDH1A1P2RY12KDM4ENPSR1 | |
| SCHEMBL23120425 | 0.74 | KDM4E (0.40) | ALDH1A1P2RY12KDM4E | |
| SCHEMBL30999852 | 0.73 | P2RY12 (0.60) | ALDH1A1P2RY12KDM4ENPSR1 | |
| SCHEMBL3922603 | 0.73 | P2RY12 (0.77) | P2RY12 | |
| SCHEMBL5062114 | 0.72 | KHK (0.41) | ALDH1A1P2RY12KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312208-A1 | Pyridine Analogues | ASTRAZENECA AB (SE) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312208-A1 | Pyridine Analogues | P2RY12, P2RY11, P2RY1 | ALDH1A1 1274/4885P2RY12 1/4885ACACB 4334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.