Ribostamycin

Ribostamycin

SCHEMBL48820

NC[C@@H]1O[C@H](O[C@@H]2[C@@H](O[C@@H]3O[C@@H](CO)[C@H](O)[C@H]3O)[C@H](O)[C@@H](N)C[C@H]2N)[C@@H](N)[C@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 1.00
TSHR P16473 2/20 0.91
HSD17B10 Q99714 1/20 0.91
LRAT O95237 2/20 0.88
MEN1 O00255 2/20 0.88
TRPV1 Q8NER1 1/20 0.88
BLM P54132 1/20 0.81
RECQL P46063 1/20 0.81
TDP1 Q9NUW8 1/20 0.81
KDM4E B2RXH2 1/20 0.78
ALOX15 P16050 1/20 0.78
GJA1 P17302 1/20 0.72
GJB2 P29033 1/20 0.72
CYP2C9 P11712 1/20 0.72
KMT2A Q03164 1/20 0.72
ALDH1A1 P00352 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ribostamycin SCHEMBL13599669 1.00 LMNA (1.00) LMNATSHRHSD17B10LRATMEN1
Ribostamycin SCHEMBL19944115 1.00 LMNA (1.00) LMNATSHRHSD17B10LRATMEN1
Ribostamycin SCHEMBL13605470 1.00 LMNA (1.00) LMNATSHRHSD17B10LRATMEN1
Ribostamycin SCHEMBL15432715 1.00 LMNA (1.00) LMNATSHRHSD17B10LRATMEN1
SCHEMBL19619289 1.00 LMNA (1.00) LMNATSHRHSD17B10LRATMEN1
SCHEMBL19619262 1.00 LMNA (1.00) LMNATSHRHSD17B10LRATMEN1
SCHEMBL17321247 1.00 LMNA (1.00) LMNATSHRHSD17B10LRATMEN1
SCHEMBL16882157 1.00 LMNA (1.00) LMNATSHRHSD17B10LRATMEN1
Ribostamycin SCHEMBL20530016 1.00 LMNA (1.00) LMNATSHRHSD17B10LRATMEN1
Ribostamycin SCHEMBL48819 1.00 LMNA (1.00) LMNATSHRHSD17B10LRATMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6586 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4744727-A2 SYSTEMS FOR TREATING PULMONARY INFECTIONS Insmed Incorporated (US) 2026-05-20 EP claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
US-20260096989-A1 LARGE-SCALE MANUFACTURING METHODS FOR AMINOGLYCOSIDES INSMED INCORPORATED (US) 2026-04-09 US claimed
US-12576124-B2 Formulation of a conjugate of a tubulysin analog to a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD (CN) 2026-03-17 US claimed
EP-4331675-B1 SYSTEMS FOR TREATING PULMONARY INFECTIONS INSMED INC (US) 2026-01-28 EP claimed
US-20250359910-A1 Implant of Osteostimulative Material BONE SOLUTIONS INC (US) 2025-11-27 US claimed
US-20250339551-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE DIFFERENT FUNCTIONAL SMALL MOLECULES FOR ENHANCED TREATMENT OF REFRACTORY DISEASES HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) 2025-11-06 US claimed
EP-4642492-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE FUNCTIONAL SMALL MOLECULE COMPOUNDS FOR ENHANCED TREATMENT OF REFRACTORY DISEASES Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
EP-4642484-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
US-12454675-B2 Method of increasing protein yield in mammalian cells in serum-free culture medium AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2025-10-28 US claimed
US-4351830-A Polymeric compound, MF-300, with protective activity against bacterial infections and its preparation MEIJI SEIKA KAISHA, LTD. (JP) 1982-09-28 US claimed
US-4180655-A ANTITUMOR AND ANTILEUKEMIA AGENTS Suami, Tetsuo (JP) 1979-12-25 US claimed
US-4170641-A 1-N-(ω-aminoalkanesulfonyl) derivative of aminoglycosidic antibiotic and process for preparation thereof MEIJI SEIKA KAISHA, LTD. (JP) 1979-10-09 US claimed
US-4122171-A AMINOGLYCOSIDE ANTIBIOTICS, D-GLUCARO-1,5-LACTAM NEIJI SEIKA KAISHA, LTD. (JP) 1978-10-24 US claimed
US-4065615-A Deoxyaminoglycoside antibiotic derivatives TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-12-27 US claimed
US-4060682-A Process for the synthetic production of 3-deoxy derivative of an aminoglycosidic antibiotic MEIJI SEIKA KAISHA, LTD. (JA) 1977-11-29 US claimed
US-4008218-A MULTISTAGE MEIJI SEIKI KAISHA, LTD. (JA) 1977-02-15 US claimed
US-3965089-A Process for the production of a cyclic ureido-derivative of a deoxystreptamine-containing antibiotic and products thereof ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) 1976-06-22 US claimed
US-3962429-A GLUCOSACCHARIC ACID CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) 1976-06-08 US claimed
US-3948882-A ANTIBIOTIC ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) 1976-04-06 US claimed