Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 18/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343000 | 1.00 | CCR9 (0.58) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL14065193 | 0.92 | LMNA (0.57) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL4779285 | 0.90 | CCR9 (0.62) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL343917 | 0.90 | CCR9 (0.62) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL344027 | 0.89 | CCR9 (0.56) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL14073658 | 0.89 | LMNA (0.49) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL344292 | 0.87 | CCR9 (0.61) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL344293 | 0.87 | CCR9 (0.61) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL342106 | 0.87 | CCR9 (0.66) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL342107 | 0.87 | CCR9 (0.66) | CCR9LMNAHTTTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008374-A2 | CCR2 INHIBITORS AND METHODS OF USE THEREOF | CHEMOCENTRYX, INC. (US) | 2008-01-17 | — | — | WO | claimed |