Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 5/20 | 0.58 |
| ▸ | ADK | P55263 | 1/20 | 0.52 |
| ▸ | ATR | Q13535 | 4/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3760382 | 0.94 | NOS1 (0.66) | NOS1ADKATRROCK2ROCK1 | |
| SCHEMBL3765490 | 0.88 | NOS1 (0.70) | NOS1ADK | |
| SCHEMBL3756802 | 0.82 | NOS1 (0.66) | NOS1ADKATR | |
| SCHEMBL3764506 | 0.81 | NOS1 (0.63) | NOS1ADKROCK2ROCK1 | |
| SCHEMBL3765371 | 0.79 | NOS1 (0.75) | NOS1ADKMTOR | |
| SCHEMBL3761946 | 0.78 | NOS1 (0.73) | NOS1ADKMTOR | |
| SCHEMBL3767213 | 0.78 | NOS1 (0.64) | NOS1ATRMTOR | |
| SCHEMBL3763269 | 0.77 | NOS1 (0.72) | NOS1ADKATRMTOR | |
| SCHEMBL3757061 | 0.77 | NOS1 (0.72) | NOS1ADKMTOR | |
| SCHEMBL3765366 | 0.77 | NOS1 (0.72) | NOS1ADKATRMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009079-A2 | SUBSTITUTED PTERIDINES USEFUL FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-01-24 | — | — | WO | claimed |