Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | FADS1 | O60427 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.35 |
| ▸ | F10 | P00742 | 4/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882621 | 0.91 | MAOA (0.46) | MAOAFADS1ITGB3PRSS1PRSS2 | |
| SCHEMBL4882488 | 0.85 | MAOA (0.48) | MAOAFADS1F10GRM2 | |
| SCHEMBL4883289 | 0.82 | MAOA (0.66) | MAOAFADS1F10 | |
| SCHEMBL4879580 | 0.82 | MAOA (0.46) | MAOAFADS1ITGB3PRSS1PRSS2 | |
| SCHEMBL4880152 | 0.81 | MAOA (0.59) | MAOAF10 | |
| SCHEMBL5762328 | 0.78 | GRM2 (0.53) | MAOAFADS1F10GRM2 | |
| SCHEMBL13515448 | 0.78 | MAOA (0.50) | MAOAFADS1F10 | |
| SCHEMBL3045229 | 0.76 | MAOA (0.51) | MAOAFADS1F10 | |
| SCHEMBL4882419 | 0.76 | MAOA (0.53) | MAOAITGB3PRSS1PRSS2ITGA2B | |
| SCHEMBL2798690 | 0.75 | GRM2 (0.52) | MAOAFADS1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080090884-A1 | ANTIMICROBIAL [3.1.0] BICYCLOHEXYLPHENYL- OXAZOLIDINONE DERIVATIVES AND ANALOGUES | PFIZER INC | 2008-04-17 | — | — | US | claimed |
| US-20050192325-A1 | Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues | RENSLO ADAM (US) | 2005-09-01 | — | — | US | claimed |
| US-20080090884-A1 | ANTIMICROBIAL [3.1.0] BICYCLOHEXYLPHENYL- OXAZOLIDINONE DERIVATIVES AND ANALOGUES | PFIZER INC | 2008-04-17 | — | — | US | disclosed |
| US-7279494-B2 | Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues | PFIZER INC. (US) | 2007-10-09 | — | — | US | disclosed |
| US-20050192325-A1 | Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues | RENSLO ADAM (US) | 2005-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192325-A1 | Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues | OXA1L, CYP51A1, CYP2C19 | MAOA 1957/4885FADS1 2765/4885ITGB3 1213/4885 |
| US-20080090884-A1 | ANTIMICROBIAL [3.1.0] BICYCLOHEXYLPHENYL- OXAZOLIDINONE DERIVATIVES AND ANALOGUES | OXA1L, CYP51A1, CYP2C19 | MAOA 1931/4885FADS1 2689/4885ITGB3 1187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.