SCHEMBL4882722

SCHEMBL4882722

CC[Al](CC)CCCC=O

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
HIF1A Q16665 1/20 0.45
ALDH1A1 P00352 2/20 0.41
FAAH O00519 2/20 0.41
TRPV1 Q8NER1 2/20 0.41
TDP1 Q9NUW8 2/20 0.33
MAPK1 P28482 1/20 0.33
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6338673 0.83
SCHEMBL7590459 0.82 TSHR (0.55) TSHRHIF1AALDH1A1FAAHTRPV1
SCHEMBL129074 0.82 TSHR (0.62) TSHRHIF1AALDH1A1FAAHTRPV1
SCHEMBL7796721 0.78 TSHR (0.65) TSHRHIF1AALDH1A1FAAHTRPV1
SCHEMBL10455525 0.78 TSHR (0.65) TSHRHIF1AALDH1A1FAAHTRPV1
SCHEMBL28801153 0.74 TSHR (0.50) TSHRALDH1A1MAPT
SCHEMBL9796817 0.73 TSHR (0.73) TSHRHIF1AALDH1A1FAAHTRPV1
SCHEMBL1425143 0.73 HIF1A (0.39) TSHRHIF1AALDH1A1FAAHTRPV1
SCHEMBL2142520 0.72
SCHEMBL7590728 0.72 TSHR (0.55) TSHRHIF1AALDH1A1FAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0283176-B1 PROCESS FOR PRODUCING ALUMINA- BASED FIBER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-12-18 EP claimed
EP-0283176-A1 Process for producing alumina- based fiber SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-09-21 EP claimed
CN-108884282-B Polyethylene and molded article thereof 日本聚乙烯株式会社 2021-06-08 CN disclosed
EP-0952489-B1 Positive photosensitive resin composition FUJIFILM CORP (JP) 2014-08-13 EP disclosed
US-20080125556-A1 Copolymerizing two norbornene monomers, one having a pendant trimethylsilyl or timethylsilylmethyl group, and the other having optional pendant halogen or alkyl groups in the presence of a palladium-based multicomponent catalyst containing palladium, phosphorus, ionic boron and ionic aluminum compounds JSR CORPORATION (JP) 2008-05-29 US disclosed
US-6846610-B2 Positive photosensitive resin composition FUJI PHOTO FILM CO., LTD. (JP) 2005-01-25 US disclosed
US-6806022-B1 PHOTORESISTS COMPRISING MIXTURES OF ADDITION POLYMERS, ACID GENERATORS, T-BUTYL CHOLATE, BASES, SURFACTANTS AND SOLVENTS, USED TO FORM SEMICONDUCTORS AND INTEGRATED CIRCUITS FUJI PHOTO FILM CO., LTD. (JP) 2004-10-19 US disclosed
US-20030138727-A1 Positive photosensitive resin composition FUJI PHOTO FILM CO., LTD. 2003-07-24 US disclosed
EP-0694563-B1 Olefin polymerization catalyst and process for preparing polyolefins NIPPON MITSUBISHI OIL CORP (JP) 2002-10-30 EP disclosed
EP-0808849-B1 Process for the production of ethylenic polymers SHOWA DENKO KK (JP) 2001-12-19 EP disclosed
US-6111040-A Process for the production of olefinic polymers NIPPON MITSUBISHI OIL CORPORATION (JP) 2000-08-29 US disclosed
US-4384984-A Titanium catalyst for polymerizing olefins STAUFFER CHEMICAL COMPANY (US) 1983-05-24 US disclosed
US-4382019-A Purified catalyst support STAUFFER CHEMICAL COMPANY (US) 1983-05-03 US disclosed
EP-0072165-A1 Improved process for preparing ethylene polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-02-16 EP disclosed
EP-0072035-A2 Process for producing polyolefins SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-02-16 EP disclosed
US-4364853-A COORDINATION CATALYST STAUFFER CHEMICAL COMPANY (US) 1982-12-21 US disclosed
US-4364851-A COORDINATION CATALYSTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-12-21 US disclosed
US-4354959-A ORGANOALUMINUM-TITANIUM HALIDE-MAGNESIUM OR MANGANESE COMPOUND CONTAINING HALOGEN TREATED WITH AN ETHER STAUFFER CHEMICAL COMPANY (US) 1982-10-19 US disclosed
US-4080491-A CATALYST CONTAINS ORGANOMETALLIC COMPOUND AND THE REACTION PRODUCT OF TUNGSTEN OR MOLYBDENUM OXIDE AND A PHOSPHOROUS HALIDE OR OXYHALIDE SHOWA DENKO K.K. (JA) 1978-03-21 US disclosed
US-3953541-A Process for preparation of polyolefin graft copolymers MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) 1976-04-27 US disclosed