SCHEMBL28801153

SCHEMBL28801153

C=CCCC[Al](CC)CC

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
ALDH1A1 P00352 2/20 0.50
LMNA P02545 1/20 0.30
LPAR2 Q9HBW0 1/20 0.30
LPAR3 Q9UBY5 1/20 0.30
TRPA1 O75762 1/20 0.30
ABCC4 O15439 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18585513 0.90 TSHR (0.54) TSHRALDH1A1LMNALPAR2LPAR3
SCHEMBL20136536 0.90 TSHR (0.54) TSHRALDH1A1LMNALPAR2LPAR3
SCHEMBL29776172 0.90 TSHR (0.54) TSHRALDH1A1LMNALPAR2LPAR3
SCHEMBL20550277 0.85 TSHR (0.54) TSHRALDH1A1LMNALPAR2LPAR3
SCHEMBL20138398 0.85 TSHR (0.54) TSHRALDH1A1LMNALPAR2LPAR3
SCHEMBL18586089 0.83 ALDH1A1 (0.45) TSHRALDH1A1LMNALPAR2LPAR3
SCHEMBL17866190 0.75 TSHR (0.46) TSHRALDH1A1LMNALPAR2LPAR3
SCHEMBL4882722 0.74 TSHR (0.50) TSHRALDH1A1MAPT
SCHEMBL18585366 0.73 TSHR (0.65) TSHRALDH1A1LMNALPAR2LPAR3
SCHEMBL20550666 0.73 TSHR (0.65) TSHRALDH1A1LMNALPAR2LPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108174605-B Process for the polymerization of olefins SABIC环球技术有限责任公司 2021-03-26 CN disclosed
CN-109937213-A The method that agent prepares polyolefin is reduced by discontinuously adding thermal runaway SABIC环球技术有限责任公司 2019-06-25 CN disclosed
CN-108174605-A For the method for olefinic polymerization SABIC环球技术有限责任公司 2018-06-15 CN disclosed
CN-108137718-A PROCESS FOR THE POLYMERIZATION OF OLEFINS SABIC环球技术有限责任公司 2018-06-08 CN disclosed
CN-108137717-A For the method for olefinic polymerization SABIC环球技术有限责任公司 2018-06-08 CN disclosed
CN-102741302-B Compressible liquid thinner in polyolefin polymerization Chevron Phillips Chemical Co.,L.P. (US) 2016-04-20 CN disclosed
CN-102741302-A Compressible liquid diluent in polyolefin polymerization CHEVRON PHILLIPS CHEMICAL CO 2012-10-17 CN disclosed