Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.81 |
| ▸ | PPARG | P37231 | 7/20 | 0.81 |
| ▸ | PPARD | Q03181 | 7/20 | 0.81 |
| ▸ | PPARA | Q07869 | 7/20 | 0.81 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.81 |
| ▸ | TSHR | P16473 | 4/20 | 0.81 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.81 |
| ▸ | FABP4 | P15090 | 3/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.81 |
| ▸ | TLR2 | O60603 | 2/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.81 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.81 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.81 |
| ▸ | ESR1 | P03372 | 1/20 | 0.81 |
| ▸ | PDE4A | P27815 | 1/20 | 0.81 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nonadecanoic Acid SCHEMBL28051188 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Behenic Acid SCHEMBL19638067 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL6982109 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL28174557 | 0.95 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL27643487 | 0.95 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL28926388 | 0.95 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL18917450 | 0.93 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Heptanoate SCHEMBL17092950 | 0.93 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL9398080 | 0.93 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL9576931 | 0.93 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624887-A | Heat-resistant low-dielectric-constant glass fiber reinforced PA66 material and preparation method thereof | 中广核俊尔（上海）新材料有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-109370509-A | A kind of sealant and preparation method that low modulus high elongation rate high thixotropic is ageing-resistant | 广东菊兰新型材料科技有限公司 | 2019-02-22 | — | — | CN | claimed |
| CN-109054727-A | A kind of sealant and preparation method that low modulus high elongation rate Self-leveling is ageing-resistant | 广东菊兰新型材料科技有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-106967259-A | A kind of composite flame-proof floor | 王秀梅 | 2017-07-21 | — | — | CN | claimed |
| CN-117624887-A | Heat-resistant low-dielectric-constant glass fiber reinforced PA66 material and preparation method thereof | 中广核俊尔（上海）新材料有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-114806019-B | Polymer-based composite mold material and preparation method thereof | 河北工业大学 | 2023-07-07 | — | — | CN | disclosed |
| CN-114806019-A | Composite die material based on high polymer and preparation method thereof | 河北工业大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-107189304-B | A kind of low resilience memory foam material and preparation method thereof | 青岛科技大学 | 2019-05-10 | — | — | CN | disclosed |
| CN-109476804-A | flame retardant adhesives and sealants with improved mechanical properties | SIKA技术股份公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-109476133-A | Calcium carbonate as cavitating agent for biaxially oriented polypropylene films | OMYA国际股份公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-208554431-U | A kind of successive reaction sanding apparatus modified for nanometer calcium carbonate surface | 广州大学 | 2019-03-01 | — | — | CN | disclosed |
| CN-109370509-A | A kind of sealant and preparation method that low modulus high elongation rate high thixotropic is ageing-resistant | 广东菊兰新型材料科技有限公司 | 2019-02-22 | — | — | CN | disclosed |
| US-20080194749-A1 | Flame Retardant Polymer Composition Comprising Nanofillers | BOREALIS TECHNOLOGY OY (FI) | 2008-08-14 | — | — | US | disclosed |
| WO-2005021641-A1 | FLAME RETARDANT POLYMER COMPOSITION COMPRISING NANOFILLERS | BOREALIS TECHNOLOGY OY (FI) | 2005-03-10 | — | — | WO | disclosed |
| EP-1512718-A1 | Flame retardant polymer composition comprising nanofillers | Borealis Technology Oy (FI) | 2005-03-09 | — | — | EP | disclosed |
| EP-0137883-B1 | END-CAPPING CATALYST FOR FORMING ALCOXY-FUNCTIONAL ONE COMPONENT RTV COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1989-02-15 | — | — | EP | disclosed |
| US-4528324-A | Process for producing RTV silicone rubber compositions using a devolatilizing extruder | GENERAL ELECTRIC COMPANY (US) | 1985-07-09 | — | — | US | disclosed |
| US-4515932-A | ROOM TEMPERATURE VULCANIZATION | GENERAL ELECTRIC COMPANY (US) | 1985-05-07 | — | — | US | disclosed |
| EP-0137883-A1 | End-capping catalyst for forming alcoxy-functional one component RTV compositions | GENERAL ELECTRIC COMPANY (US) | 1985-04-24 | — | — | EP | disclosed |
| US-3960802-A | Process for the manufacture of a one-component room-temperature vulcanizable silicone composition | GENERAL ELECTRIC COMPANY (US) | 1976-06-01 | — | — | US | disclosed |