Hydrochloric Acid

Hydrochloric Acid

SCHEMBL4883167

O=C(NC[P+](c1ccccc1)(c1ccccc1)c1ccccc1)C12CC3CC(CC(C3)C1)C2.[Cl-]

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.61
HSD11B1 P28845 5/20 0.52
P2RX7 Q99572 1/20 0.51
KMT2A Q03164 3/20 0.51
CYP17A1 P05093 2/20 0.51
CYP19A1 P11511 2/20 0.51
MEN1 O00255 2/20 0.51
ALDH1A1 P00352 1/20 0.51
POLB P06746 1/20 0.50
MAPK1 P28482 1/20 0.48
HTT P42858 2/20 0.48
KDM4E B2RXH2 1/20 0.48
NPSR1 Q6W5P4 1/20 0.47
CYP2D6 P10635 1/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21523099 0.80 HPGD (0.61) HPGDHSD11B1P2RX7KMT2ACYP17A1
SCHEMBL21523098 0.80 HPGD (0.61) HPGDHSD11B1P2RX7KMT2ACYP17A1
SCHEMBL3455848 0.76 HPGD (1.00) HPGDHSD11B1P2RX7KMT2ACYP17A1
SCHEMBL21523077 0.72 HPGD (0.62) HPGDHSD11B1P2RX7KMT2ACYP17A1
SCHEMBL13840110 0.72 SMN1; SMN2 (0.57) HPGDKMT2ACYP17A1CYP19A1MEN1
Hydrochloric Acid SCHEMBL21523063 0.71 HPGD (0.50) HPGDHSD11B1P2RX7KMT2ACYP17A1
SCHEMBL17983472 0.71 HTT (0.54) HPGDHSD11B1KMT2ACYP17A1CYP19A1
SCHEMBL21531588 0.71 HPGD (0.49) HPGDHSD11B1P2RX7KMT2AMEN1
SCHEMBL25190275 0.70 HPGD (0.81) HPGDHSD11B1P2RX7KMT2ACYP17A1
SCHEMBL8621356 0.70 HPGD (0.76) HPGDHSD11B1P2RX7KMT2ACYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1976388-A1 ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT CTT GROUP INC. (CA) 2008-10-08 EP claimed
US-20080199502-A1 Antimicrobial Solution Comprising a Metallic Salt and a Surfactant CTT GROUP INC. (CA) 2008-08-21 US claimed
WO-2006105669-A1 ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT CTT GROUP INC. (CA) 2006-10-12 WO claimed
US-20150201622-A1 NEW ANTIMICROBIAL COMPOSITIONS AND USES THEREOF CTT GROUP INC (CA) 2015-07-23 US disclosed
EP-1976388-A1 ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT CTT GROUP INC. (CA) 2008-10-08 EP disclosed
US-20080199502-A1 Antimicrobial Solution Comprising a Metallic Salt and a Surfactant CTT GROUP INC. (CA) 2008-08-21 US disclosed
WO-2006105669-A1 ANTIMICROBIAL SOLUTION COMPRISING A METALLIC SALT AND A SURFACTANT CTT GROUP INC. (CA) 2006-10-12 WO disclosed