Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.46 |
| ▸ | PPARA | Q07869 | 12/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882229 | 0.93 | PPARG (0.53) | PPARGPPARAITGB3ITGA2BPPARD | |
| SCHEMBL4654004 | 0.92 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL4878974 | 0.87 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL4654894 | 0.86 | PPARG (0.62) | PPARGPPARAPPARD | |
| SCHEMBL4884983 | 0.86 | PPARG (0.47) | PPARGPPARAPPARD | |
| SCHEMBL4654924 | 0.81 | PPARG (0.59) | PPARGPPARAPPARD | |
| SCHEMBL4155845 | 0.79 | PPARG (0.71) | PPARGPPARAPPARD | |
| SCHEMBL4654982 | 0.78 | PPARG (0.53) | PPARGPPARAPPARD | |
| SCHEMBL4654923 | 0.78 | PPARG (0.53) | PPARGPPARAPPARD | |
| SCHEMBL4652871 | 0.78 | PPARG (0.49) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113974-A1 | Heterocyclic Oxime Compounds, A Process For Their Preparation And Pharmaceutical Compositions Containing Them. | LES LABORATOIRES SERVIER (FR) | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113974-A1 | Heterocyclic Oxime Compounds, A Process For Their Preparation And Pharmaceutical Compositions Containing Them. | CBR1, CYP3A7, CYP2C9 | PPARG 1185/4885PPARA 1634/4885ITGB3 1110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.