Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | NPC1 | O15118 | 9/20 | 0.82 |
| ▸ | RAB9A | P51151 | 9/20 | 0.82 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11965041 | 0.95 | PKM (0.90) | PKMTP53NPC1RAB9AATAD2 | |
| SCHEMBL9612006 | 0.95 | PKM (0.90) | PKMTP53NPC1RAB9AATAD2 | |
| SCHEMBL714484 | 0.91 | NPC1 (1.00) | PKMTP53NPC1RAB9AATAD2 | |
| SCHEMBL4883972 | 0.87 | TP53 (0.75) | PKMTP53NPC1RAB9AATAD2 | |
| SCHEMBL4876686 | 0.87 | NPC1 (0.79) | PKMTP53NPC1RAB9AATAD2 | |
| SCHEMBL2766462 | 0.85 | PKM (0.74) | PKMTP53NPC1RAB9AATAD2 | |
| SCHEMBL8360193 | 0.84 | PKM (0.71) | PKMTP53NPC1RAB9AATAD2 | |
| Neovadrine SCHEMBL22799863 | 0.84 | PKM (0.71) | PKMTP53NPC1RAB9AATAD2 | |
| SCHEMBL987340 | 0.84 | PKM (0.71) | PKMTP53NPC1RAB9AATAD2 | |
| SCHEMBL38657585 | 0.83 | NPC1 (0.72) | PKMTP53NPC1RAB9AATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116769181-A | Zinc-based molecular crystal blue-green light material and preparation method thereof | 江西省科学院应用化学研究所 | 2023-09-19 | — | — | CN | claimed |
| CN-105642355-A | Crystalline polyacid complex-based composite Fischer-Tropsch catalyst and preparation method thereof | 上海大学 | 2016-06-08 | — | — | CN | claimed |
| CN-103059049-B | A kind of pure red phosphor crystal material and its production and use | FUJIAN INSTITUTE OF RESEARCH ON THE STRUCTURE OF MATTER, CHINESE ACADEMY OF SCIENCES (CN) | 2016-02-17 | — | — | CN | claimed |
| CN-102516984-B | A kind of orange red phosphor crystal material and its production and use | FUJIAN INSTITUTE OF RESEARCH ON THE STRUCTURE OF MATTER, CHINESE ACADEMY OF SCIENCES (CN) | 2015-09-16 | — | — | CN | claimed |
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2008-01-17 | — | — | US | claimed |
| CN-117886809-A | Oxadiazole viologen compound, preparation method and application thereof in flow battery | 内蒙古科技大学 | 2024-04-16 | — | — | CN | disclosed |
| CN-116769181-A | Zinc-based molecular crystal blue-green light material and preparation method thereof | 江西省科学院应用化学研究所 | 2023-09-19 | — | — | CN | disclosed |
| CN-105642355-A | Crystalline polyacid complex-based composite Fischer-Tropsch catalyst and preparation method thereof | 上海大学 | 2016-06-08 | — | — | CN | disclosed |
| CN-103059049-B | A kind of pure red phosphor crystal material and its production and use | FUJIAN INSTITUTE OF RESEARCH ON THE STRUCTURE OF MATTER, CHINESE ACADEMY OF SCIENCES (CN) | 2016-02-17 | — | — | CN | disclosed |
| CN-103059049-B | A kind of pure red phosphor crystal material and its production and use | FUJIAN INSTITUTE OF RESEARCH ON THE STRUCTURE OF MATTER, CHINESE ACADEMY OF SCIENCES (CN) | 2016-02-17 | — | — | CN | disclosed |
| CN-102516984-B | A kind of orange red phosphor crystal material and its production and use | FUJIAN INSTITUTE OF RESEARCH ON THE STRUCTURE OF MATTER, CHINESE ACADEMY OF SCIENCES (CN) | 2015-09-16 | — | — | CN | disclosed |
| CN-102516984-B | A kind of orange red phosphor crystal material and its production and use | FUJIAN INSTITUTE OF RESEARCH ON THE STRUCTURE OF MATTER, CHINESE ACADEMY OF SCIENCES (CN) | 2015-09-16 | — | — | CN | disclosed |
| CN-102516984-A | Orange-red phosphorescent crystal material, as well as preparation method and use thereof | FUJIAN MATTER STRUCTURE | 2012-06-27 | — | — | CN | disclosed |
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2008-01-17 | — | — | US | disclosed |
| WO-2007149395-A2 | 2,5-SUBSTITUTED OXAZOLE DERIVATIVES AS PROTEIN KINASE INHIBITORS FOR THE TREATMENT OF CANCER | AMPHORA DISCOVERY CORPORATION (US) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | ATP5ME, ATP5MG, ATP5MK | PKM 1059/4885TP53 2741/4885NPC1 2981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.