Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.60 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.59 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.59 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.59 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.59 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.59 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7174826 | 0.81 | HRH4 (0.61) | HRH4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4888727 | 0.80 | HRH4 (0.47) | HRH4HRH3 | |
| SCHEMBL7202375 | 0.77 | GRIN2D (0.71) | HRH4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6130833 | 0.75 | HRH4 (1.00) | HRH4HRH3NPC1RAB9A | |
| SCHEMBL7172096 | 0.75 | GRIN2D (0.68) | HRH4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7162199 | 0.75 | GRIN2D (0.74) | HRH4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7176141 | 0.74 | HRH4 (0.70) | HRH4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4813274 | 0.74 | GRIN2D (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7167078 | 0.74 | GRIN2D (0.57) | HRH4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7159245 | 0.73 | GRIN2D (1.00) | HRH4GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080300276-A1 | Heterocyclic Carboxylic Acide Amide Derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2008-12-04 | — | — | US | claimed |
| EP-1771437-A1 | NEW HETEROCYCLIC CARBOXYLIC ACID AMIDE DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2007-04-11 | — | — | EP | claimed |
| WO-2006010969-A1 | NEW HETEROCYCLIC CARBOXYLIC ACID AMIDE DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-02-02 | — | — | WO | claimed |
| US-20080300276-A1 | Heterocyclic Carboxylic Acide Amide Derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2008-12-04 | — | — | US | disclosed |
| EP-1771437-A1 | NEW HETEROCYCLIC CARBOXYLIC ACID AMIDE DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010969-A1 | NEW HETEROCYCLIC CARBOXYLIC ACID AMIDE DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300276-A1 | Heterocyclic Carboxylic Acide Amide Derivatives | HCAR2, GRIN1, HCAR1 | HRH4 16/4885GRIN2D 19/4885GRIN3B 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.