SCHEMBL4884408

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4892226	0.89	NQO2 (0.39)	HSP90AA1CA12CA1CA2CA7
	SCHEMBL6662495	0.89	PPARG (0.52)	PPARGPPARAHSP90AA1CA12CA1
	SCHEMBL3692384	0.88	PPARG (0.41)	PPARGPPARAHSP90AA1EGFRCA12
	SCHEMBL27589635	0.85	PPARG (0.47)	PPARGPPARAHSP90AA1CA12CA1
	SCHEMBL4893266	0.83	NQO2 (0.39)	PPARGPPARAHSP90AA1EGFRCA12
	SCHEMBL4898444	0.82	NQO2 (0.47)	EGFR
	SCHEMBL4616924	0.78	ALDH1A1 (0.43)	EGFR
	SCHEMBL14110330	0.76	ALDH1A1 (0.42)	EGFR
	SCHEMBL14110344	0.76	HMGCR (0.43)	EGFR
	SCHEMBL5106706	0.75	F2 (0.41)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.