Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.55 |
| ▸ | CNR1 | P21554 | 3/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 5/20 | 0.44 |
| ▸ | F9 | P00740 | 3/20 | 0.44 |
| ▸ | F11 | P03951 | 3/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882979 | 0.86 | CNR2 (0.53) | CNR2CNR1PPARGADORA2AF7 | |
| SCHEMBL3894629 | 0.82 | CNR2 (0.57) | CNR2CNR1ADORA2ANAMPTALDH1A1 | |
| SCHEMBL4876418 | 0.80 | CNR2 (0.53) | CNR2CNR1PPARGADORA2APRSS1 | |
| SCHEMBL4876419 | 0.78 | CNR2 (0.57) | CNR2CNR1ADORA2ANR1H4EPHX2 | |
| SCHEMBL14294157 | 0.78 | PPARG (0.46) | PPARGF7F10F2NR1H4 | |
| SCHEMBL3890880 | 0.77 | CNR2 (0.53) | CNR2CNR1PPARGADORA2ANAMPT | |
| SCHEMBL17865785 | 0.77 | ADORA2A (0.59) | CNR2CNR1ADORA2APRSS1NR1H4 | |
| SCHEMBL27214505 | 0.77 | PPARG (0.76) | CNR2CNR1PPARGADORA2ANR1H4 | |
| SCHEMBL3893570 | 0.76 | MAPT (0.57) | CNR2CNR1ALDH1A1HPGD | |
| SCHEMBL23471200 | 0.74 | PRSS1 (0.44) | CNR2CNR1ADORA2APRSS1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051416-A1 | Novel Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-28 | — | — | US | disclosed |
| US-20080051416-A1 | Novel Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-28 | — | — | US | disclosed |
| US-20080051416-A1 | Novel Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-28 | — | — | US | disclosed |
| EP-1805132-A2 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006110173-A2 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051416-A1 | Novel Compounds | MAPK1, MAPKAPK2, MAPK6 | CNR2 1310/4885CNR1 981/4885PPARG 900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.