Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4893681 | 0.99 | HCAR2 (0.41) | HCAR2ATMZDHHC20ZDHHC2NAAA | |
| SCHEMBL4893688 | 0.89 | HCAR2 (0.37) | HCAR2ATMZDHHC20ZDHHC2TSHR | |
| SCHEMBL4891948 | 0.82 | TSHR (0.33) | ATMTSHR | |
| SCHEMBL4890618 | 0.80 | TSHR (0.36) | TSHR | |
| SCHEMBL15229292 | 0.80 | HCAR2 (0.64) | HCAR2ATMZDHHC20ZDHHC2NAAA | |
| SCHEMBL8380051 | 0.80 | HCAR2 (0.64) | HCAR2ATMZDHHC20ZDHHC2NAAA | |
| SCHEMBL3457992 | 0.80 | HCAR2 (0.64) | HCAR2ATMZDHHC20ZDHHC2NAAA | |
| SCHEMBL2903635 | 0.80 | HCAR2 (0.64) | HCAR2ATMZDHHC20ZDHHC2NAAA | |
| SCHEMBL29892 | 0.80 | HCAR2 (0.64) | HCAR2ATMZDHHC20ZDHHC2NAAA | |
| SCHEMBL1452757 | 0.80 | HCAR2 (0.64) | HCAR2ATMZDHHC20ZDHHC2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293872-A1 | ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER | HENKEL AG & CO. KGAA (DE) | 2008-11-27 | — | — | US | disclosed |
| US-20080287574-A1 | ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER | HENKEL AG & CO. KGAA (DE) | 2008-11-20 | — | — | US | disclosed |