Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4884984 | 0.99 | HCAR2 (0.42) | HCAR2ATMZDHHC20ZDHHC2TSHR | |
| SCHEMBL4893688 | 0.90 | HCAR2 (0.37) | HCAR2ATMZDHHC20ZDHHC2TSHR | |
| SCHEMBL4891948 | 0.83 | TSHR (0.33) | ATMTSHR | |
| SCHEMBL4890618 | 0.81 | TSHR (0.36) | TSHR | |
| SCHEMBL4891419 | 0.80 | TSHR (0.35) | TSHR | |
| SCHEMBL1452125 | 0.79 | HCAR2 (0.62) | HCAR2ATMZDHHC20ZDHHC2TSHR | |
| SCHEMBL28421374 | 0.79 | HCAR2 (0.67) | HCAR2ATMTDP1MAPT | |
| SCHEMBL27168435 | 0.79 | HCAR2 (0.61) | HCAR2ATMTSHRTDP1MAPT | |
| SCHEMBL4885631 | 0.78 | TSHR (0.33) | TSHR | |
| SCHEMBL15229292 | 0.78 | HCAR2 (0.64) | HCAR2ATMZDHHC20ZDHHC2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293872-A1 | ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER | HENKEL AG & CO. KGAA (DE) | 2008-11-27 | — | — | US | disclosed |
| US-20080287574-A1 | ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER | HENKEL AG & CO. KGAA (DE) | 2008-11-20 | — | — | US | disclosed |