Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 12/20 | 0.59 |
| ▸ | FYN | P06241 | 6/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4595031 | 0.82 | FYN (0.77) | RETFYNPIM1 | |
| SCHEMBL4338153 | 0.80 | RET (0.69) | RETFYNPIM1 | |
| SCHEMBL4594447 | 0.79 | RET (0.79) | RETFYNPIM1CYP1A2CYP3A4 | |
| SCHEMBL4595252 | 0.73 | FYN (0.73) | RETFYNPIM1 | |
| SCHEMBL4342469 | 0.73 | FYN (0.76) | RETFYNPIM1CYP1A2CYP3A4 | |
| SCHEMBL4594876 | 0.73 | PIM1 (0.75) | RETFYNPIM1 | |
| SCHEMBL4338947 | 0.72 | RET (0.71) | RETFYNPIM1 | |
| SCHEMBL4345361 | 0.72 | RET (0.74) | RETFYNPIM1 | |
| SCHEMBL4331369 | 0.72 | RET (0.76) | RETFYNPIM1 | |
| SCHEMBL4331120 | 0.72 | PIM1 (0.74) | RETFYNPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080039455-A1 | PYRAZOLOPYRIMIDINES AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2008-02-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039455-A1 | PYRAZOLOPYRIMIDINES AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME | DPYD, FLT1, PDXK | RET 911/4885FYN 151/4885PIM1 400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.