Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.47 |
| ▸ | CNR1 | P21554 | 9/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4885370 | 1.00 | CNR2 (0.47) | CNR2CNR1FAAHPPARATAS1R3 | |
| SCHEMBL28967967 | 0.85 | CNR1 (0.63) | CNR2CNR1FAAH | |
| SCHEMBL5520144 | 0.84 | CNR1 (0.61) | CNR2CNR1FAAH | |
| SCHEMBL5520146 | 0.84 | CNR1 (0.61) | CNR2CNR1FAAH | |
| SCHEMBL11051266 | 0.78 | MAOB (0.39) | — | |
| SCHEMBL11816978 | 0.78 | MAOB (0.39) | — | |
| SCHEMBL5973602 | 0.77 | ALDH1A1 (0.53) | CNR2CNR1FAAHPPARATAS1R3 | |
| SCHEMBL5973606 | 0.77 | ALDH1A1 (0.53) | CNR2CNR1FAAHPPARATAS1R3 | |
| SCHEMBL5188191 | 0.76 | PPARA (0.48) | CNR2CNR1FAAHPPARATAS1R3 | |
| SCHEMBL9398170 | 0.76 | PPARA (0.64) | CNR2CNR1FAAHPPARAPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140341909-A1 | CONJUGATION OF BIOMOLECULES USING DIELS-ALDER CYCLOADDITION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERV (US) | 2014-11-20 | — | — | US | disclosed |
| US-20080008709-A1 | Conjugation of biomolecules using Diels-Alder cycloaddition | The Government of the U.S. as represented by the Secretary of the Dept. of Health and Human | 2008-01-10 | — | — | US | disclosed |
| US-7211445-B2 | Immunology, diagnosis, therapy; complex of carbohydrate and protein; immobilization | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2007-05-01 | — | — | US | disclosed |
| US-20040082067-A1 | Immunology, diagnosis, therapy; complex of carbohydrate and protein; immobilization | THE GOVERNMENT OF THE U.S.A. AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HLTH. AND HUMAN SERVICE | 2004-04-29 | — | — | US | disclosed |
| US-6673905-B2 | FOR COVALENTLY LINKING CARBOHYDRATES AND PROTEINS UNDER NEUTRAL CONDITIONS, BY ATTACHING DOUBLE BONDS TO A CARRIER PROTEIN, AND ATTACHING A CONJUGATED DIENE TO A CARBOHYDRATE HAPTEN, THEN COUPLING; VACCINES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2004-01-06 | — | — | US | disclosed |
| US-20020068818-A1 | Conjugation of biomolecules using diels-alder cycloaddition | POZSGAY VINCE (US) | 2002-06-06 | — | — | US | disclosed |
| US-20020051788-A1 | For covalently linking carbohydrates and proteins under neutral conditions, by attaching double bonds to a carrier protein, and attaching a conjugated diene to a carbohydrate hapten, then coupling; vaccines | HEALTH AND HUMAN SERVICES, DEPARTMENT OF, GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, THE | 2002-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140341909-A1 | CONJUGATION OF BIOMOLECULES USING DIELS-ALDER CYCLOADDITION | DERA, DCLRE1A, CD2BP2 | CNR2 3360/4885CNR1 3139/4885FAAH 4274/4885 |
| US-20020068818-A1 | Conjugation of biomolecules using diels-alder cycloaddition | DERA, DCLRE1A, CD2BP2 | CNR2 3360/4885CNR1 3139/4885FAAH 4274/4885 |
| US-20020051788-A1 | For covalently linking carbohydrates and proteins under neutral conditions, by attaching double bonds to a carrier protein, and attaching a conjugated diene to a carbohydrate hapten, then coupling; vaccines | DCLRE1A, DERA, LY96 | CNR2 2409/4885CNR1 2464/4885FAAH 3601/4885 |
| US-20080008709-A1 | Conjugation of biomolecules using Diels-Alder cycloaddition | DERA, DCLRE1A, CD2BP2 | CNR2 3360/4885CNR1 3139/4885FAAH 4274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.