Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.44 |
| ▸ | KDM1A | O60341 | 4/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4892063 | 0.85 | SLC6A4 (0.44) | SLC6A2SLC6A4SLC6A3HTR6CYP2D6 | |
| SCHEMBL4892069 | 0.85 | SLC6A4 (0.44) | SLC6A2SLC6A4SLC6A3HTR6CYP2D6 | |
| SCHEMBL4892079 | 0.85 | SLC6A4 (0.44) | SLC6A2SLC6A4SLC6A3HTR6CYP2D6 | |
| SCHEMBL23873360 | 0.82 | SSTR1 (0.39) | SLC6A2SLC6A4SLC6A3KDM1AHTR2A | |
| SCHEMBL26115646 | 0.82 | SSTR1 (0.39) | SLC6A2SLC6A4SLC6A3KDM1AHTR2A | |
| SCHEMBL23873361 | 0.82 | SSTR1 (0.39) | SLC6A2SLC6A4SLC6A3KDM1AHTR2A | |
| Hydrochloric Acid SCHEMBL4889742 | 0.81 | KDM1A (0.56) | KDM1AHTR2AHTR2CHTR2BSCN5A | |
| Hydrochloric Acid SCHEMBL4889743 | 0.81 | KDM1A (0.56) | KDM1AHTR2AHTR2CHTR2BSCN5A | |
| Hydrochloric Acid SCHEMBL4889749 | 0.81 | KDM1A (0.56) | KDM1AHTR2AHTR2CHTR2BSCN5A | |
| SCHEMBL19702118 | 0.81 | KDM1A (0.51) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312271-A1 | AZABENZIMIDAZOLYL COMPOUNDS | PFIZER INC. | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312271-A1 | AZABENZIMIDAZOLYL COMPOUNDS | AZI2, PAICS, UGT2B7 | SLC6A2 1043/4885SLC6A4 719/4885SLC6A3 903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.