Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR1E | P28566 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4892063 | 1.00 | SLC6A4 (0.44) | SLC6A4SLC6A3SLC6A2CYP2D6CSNK2A1 | |
| SCHEMBL4892069 | 1.00 | SLC6A4 (0.44) | SLC6A4SLC6A3SLC6A2CYP2D6CSNK2A1 | |
| SCHEMBL4885966 | 0.85 | SLC6A2 (0.44) | SLC6A4SLC6A3SLC6A2CYP2D6HTR2A | |
| SCHEMBL4892085 | 0.81 | SSTR1 (0.39) | SLC6A4SLC6A3SLC6A2CYP2D6HTR2A | |
| SCHEMBL4892077 | 0.81 | SSTR1 (0.39) | SLC6A4SLC6A3SLC6A2CYP2D6HTR2A | |
| SCHEMBL4892067 | 0.81 | SSTR1 (0.39) | SLC6A4SLC6A3SLC6A2CYP2D6HTR2A | |
| SCHEMBL5584880 | 0.80 | SLC6A4 (0.45) | SLC6A4SLC6A3SLC6A2CSNK2A1S1PR1 | |
| Hydrochloric Acid SCHEMBL4930544 | 0.76 | SLC6A2 (0.45) | SLC6A4SLC6A3SLC6A2CYP2D6HTR2A | |
| Hydrochloric Acid SCHEMBL4930560 | 0.76 | SLC6A2 (0.45) | SLC6A4SLC6A3SLC6A2CYP2D6HTR2A | |
| Hydrochloric Acid SCHEMBL4930552 | 0.76 | SLC6A2 (0.45) | SLC6A4SLC6A3SLC6A2CYP2D6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312271-A1 | AZABENZIMIDAZOLYL COMPOUNDS | PFIZER INC. | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312271-A1 | AZABENZIMIDAZOLYL COMPOUNDS | AZI2, PAICS, UGT2B7 | SLC6A4 719/4885SLC6A3 903/4885SLC6A2 1043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.