Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | UNG | P13051 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4895021 | 0.82 | EPHX2 (0.54) | EPHX2PPARGTBXAS1CYP3A4CYP2C9 | |
| SCHEMBL4665668 | 0.79 | ESR1 (0.55) | ALDH1A1ESR1PGRESR2KDM4E | |
| SCHEMBL4665675 | 0.79 | ESR1 (0.55) | ALDH1A1ESR1PGRESR2KDM4E | |
| SCHEMBL12499782 | 0.78 | AKR1C3 (0.50) | EPHX2TBXAS1CYP3A4CYP2C9MEN1 | |
| SCHEMBL12499785 | 0.78 | AKR1C3 (0.50) | EPHX2TBXAS1CYP3A4CYP2C9MEN1 | |
| SCHEMBL1579813 | 0.76 | TBXAS1 (0.48) | EPHX2PPARGTBXAS1CYP3A4CYP2C9 | |
| SCHEMBL14032639 | 0.76 | EPHX2 (0.47) | EPHX2TBXAS1CYP3A4CYP2C9MEN1 | |
| SCHEMBL20184163 | 0.76 | KDM4E (0.58) | EPHX2TBXAS1CYP3A4CYP2C9MEN1 | |
| SCHEMBL2391183 | 0.76 | KDM4E (0.58) | EPHX2TBXAS1CYP3A4CYP2C9MEN1 | |
| SCHEMBL6338925 | 0.76 | KDM4E (0.58) | EPHX2TBXAS1CYP3A4CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255078-A1 | Triphenylethylene Compounds Useful as Selective Estrogen Receptor Modulators | KATAMREDDY SUBBA REDDY | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255078-A1 | Triphenylethylene Compounds Useful as Selective Estrogen Receptor Modulators | GPER1, ESR2, ESRRG | EPHX2 2091/4885PPARG 63/4885TBXAS1 226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.