SCHEMBL4886192

SCHEMBL4886192

CCn1ccnc1C(C)c1cccc(C)c1C.Cc1cccc(C(C)c2nccn2COC(=O)OCC(F)(F)F)c1C

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.39
ALDH1A1 P00352 1/20 0.39
KMT2A Q03164 2/20 0.38
FPR2 P25090 9/20 0.37
TP53 P04637 1/20 0.32
MEN1 O00255 1/20 0.32
JMJD6 Q6NYC1 1/20 0.31
NPC1 O15118 1/20 0.31
OPRK1 P41145 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL696528 0.98 ALDH1A1 (0.35) MAPTALDH1A1KMT2AFPR2TP53
SCHEMBL696322 0.90 ALDH1A1 (0.38) MAPTALDH1A1KMT2AFPR2TP53
SCHEMBL696927 0.83 ALDH1A1 (0.35) MAPTALDH1A1KMT2AFPR2TP53
SCHEMBL696564 0.83 CYP19A1 (0.34) MAPTALDH1A1KMT2AFPR2TP53
SCHEMBL696897 0.82 ALDH1A1 (0.38) MAPTALDH1A1KMT2AFPR2TP53
SCHEMBL696323 0.82 SMN1; SMN2 (0.38) MAPTALDH1A1KMT2AFPR2TP53
SCHEMBL696999 0.82 ALDH1A1 (0.37) MAPTALDH1A1KMT2AFPR2TP53
SCHEMBL3528743 0.81 ALDH1A1 (0.35) MAPTALDH1A1KMT2AFPR2TP53
SCHEMBL697152 0.81 ALDH1A1 (0.35) MAPTALDH1A1KMT2AFPR2TP53
SCHEMBL698624 0.81 ALDH1A1 (0.35) MAPTALDH1A1KMT2AFPR2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1981853-A1 SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES Pfizer Limited (GB) 2008-10-22 EP disclosed
WO-2007083207-A1 SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES PFIZER LIMITED (GB) 2007-07-26 WO disclosed