SCHEMBL4886223

SCHEMBL4886223

CC1(Cl)C=C[CH]C=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3248404 0.76
SCHEMBL6502350 0.69
SCHEMBL5997087 0.69
SCHEMBL3697906 0.67
SCHEMBL4221128 0.66
SCHEMBL6106528 0.64
SCHEMBL4820114 0.64
SCHEMBL3019277 0.64
SCHEMBL6105504 0.64
SCHEMBL7818882 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080312271-A1 AZABENZIMIDAZOLYL COMPOUNDS PFIZER INC. 2008-12-18 US claimed
CN-114835705-A Heterocyclic compound and application thereof in medicine 杭州安道药业有限公司 2022-08-02 CN disclosed
CN-109776523-B Heterocyclic compound and application thereof in medicine 杭州安道药业有限公司 2022-04-15 CN disclosed
CN-113004271-A Indolizine derivative and application thereof in medicine 杭州安道药业有限公司 2021-06-22 CN disclosed
CN-108484598-B Indolizine derivative and application thereof in medicine 杭州安道药业有限公司 2021-03-02 CN disclosed
US-4268267-A PRINTING AND DYEING TEXTILES BAYER AKTIENGESELLSCHAFT (DE) 1981-05-19 US disclosed