SCHEMBL3697906

SCHEMBL3697906

CC1(Cl)[CH]C=CC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1245323 0.69
SCHEMBL4886223 0.67
SCHEMBL17024280 0.67
SCHEMBL6915854 0.65
SCHEMBL3248404 0.63
SCHEMBL196540 0.63
SCHEMBL3116228 0.63
SCHEMBL2078830 0.62
SCHEMBL21247921 0.62
SCHEMBL2470905 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2914589-A1 COMPOUNDS FOR USE IN THE TREATMENT OF PARASITIC DISEASES IRBM - Science Park S.p.A. (IT) 2015-09-09 EP claimed
WO-2014067985-A1 COMPOUNDS FOR USE IN THE TREATMENT OF PARASITIC DISEASES IRBM SCIENCE PARK S.P.A. (IT) 2014-05-08 WO claimed
EP-0338493-A2 Tetrahydro-4-phenylimino-3-thiophen-acetic acids Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1989-10-25 EP claimed
EP-0338494-A2 3-Anilino-2-hydroxycarbonyl-4-thiophen-acetic acids Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1989-10-25 EP claimed
EP-2914589-A1 COMPOUNDS FOR USE IN THE TREATMENT OF PARASITIC DISEASES IRBM - Science Park S.p.A. (IT) 2015-09-09 EP disclosed
WO-2014067985-A1 COMPOUNDS FOR USE IN THE TREATMENT OF PARASITIC DISEASES IRBM SCIENCE PARK S.P.A. (IT) 2014-05-08 WO disclosed
US-8481738-B2 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2013-07-09 US disclosed
US-20120122891-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO NEUROCRINE BIOSCIENCES, INC. (US) 2012-05-17 US disclosed
EP-1943234-A1 TRIAZOLE COMPOUNDS AS LIPOXYGENASE INHIBITORS Biolipox AB (SE) 2008-07-16 EP disclosed
US-20070238669-A1 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY 2007-10-11 US disclosed
WO-2007051982-A1 TRIAZOLE COMPOUNDS AS LIPOXYGENASE INHIBITORS BIOLIPOX AB (SE) 2007-05-10 WO disclosed
EP-1368300-A1 SUBSTITUTED AMINO DICARBOXYLIC ACID DERIVATIVES Bayer Aktiengesellschaft (DE) 2003-12-10 EP disclosed
WO-2002070462-A1 SUBSTITUTED AMINO DICARBOXYLIC ACID DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2002-09-12 WO disclosed
EP-0338493-A2 Tetrahydro-4-phenylimino-3-thiophen-acetic acids Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1989-10-25 EP disclosed
EP-0338494-A2 3-Anilino-2-hydroxycarbonyl-4-thiophen-acetic acids Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1989-10-25 EP disclosed