Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.46 |
| ▸ | DPP4 | P27487 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4879972 | 0.83 | GPR119 (0.50) | GPR119MCHR1DPP4 | |
| SCHEMBL4794706 | 0.80 | GPR119 (0.46) | GPR119MCHR1DPP4KCNH2DPP8 | |
| SCHEMBL4888760 | 0.80 | MCHR1 (0.47) | GPR119MCHR1DPP4KCNH2DPP8 | |
| SCHEMBL4885441 | 0.79 | MCHR1 (0.71) | GPR119MCHR1DPP4KCNH2DPP8 | |
| SCHEMBL4886218 | 0.78 | MCHR1 (0.44) | GPR119MCHR1DPP4KCNH2DPP8 | |
| SCHEMBL15205622 | 0.75 | HRH3 (0.41) | MCHR1 | |
| SCHEMBL1751227 | 0.75 | HRH3 (0.41) | MCHR1 | |
| SCHEMBL1751229 | 0.75 | HRH3 (0.41) | MCHR1 | |
| SCHEMBL2333750 | 0.71 | GPR119 (0.77) | GPR119 | |
| SCHEMBL1751868 | 0.71 | USP30 (0.36) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080085884-A1 | Melanin Concentrating Hormone Receptor-1 Antagonist Pyridinones | PFIZER INC | 2008-04-10 | — | — | US | disclosed |
| US-20080085884-A1 | Melanin Concentrating Hormone Receptor-1 Antagonist Pyridinones | PFIZER INC | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085884-A1 | Melanin Concentrating Hormone Receptor-1 Antagonist Pyridinones | MCHR1, MCHR2, MC1R | GPR119 61/4885MCHR1 1/4885DPP4 2273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.