SCHEMBL4886880

SCHEMBL4886880

OC(CN1CCN(Cc2ccccc2)CC1)C(O)(c1ccccc1)C1CCCC1

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 4/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
CHRM2 P08172 3/20 0.51
CHRM1 P11229 3/20 0.51
KDM4E B2RXH2 2/20 0.50
KCNH2 Q12809 1/20 0.47
LMNA P02545 1/20 0.47
GAA P10253 1/20 0.47
HRH1 P35367 1/20 0.46
IGF1R P08069 1/20 0.45
SIGMAR1 Q99720 1/20 0.45
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4883153 0.93 SIGMAR1 (0.49) CHRM3MEN1KMT2ACHRM2CHRM1
SCHEMBL4889873 0.88 MEN1 (0.56) CHRM3MEN1KMT2ACHRM2CHRM1
SCHEMBL4890266 0.87 MEN1 (0.58) CHRM3MEN1KMT2ACHRM2CHRM1
SCHEMBL4881797 0.87 MEN1 (0.58) CHRM3MEN1KMT2ACHRM2CHRM1
SCHEMBL4889264 0.86 TSHR (0.53) CHRM3MEN1KMT2ACHRM2CHRM1
SCHEMBL4885076 0.86 MEN1 (0.54) CHRM3MEN1KMT2ACHRM2CHRM1
SCHEMBL4889974 0.85 MEN1 (0.53) CHRM3MEN1KMT2ACHRM2CHRM1
SCHEMBL4882542 0.84 MEN1 (0.71) CHRM3MEN1KMT2ACHRM2CHRM1
SCHEMBL4889815 0.84 MEN1 (0.52) CHRM3MEN1KMT2ACHRM2CHRM1
SCHEMBL4887153 0.83 CHRM3 (0.50) CHRM3MEN1KMT2ACHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080280883-A1 Muscarinic Receptor Antagonists RANBAXY LABORATORIES LIMITED (IN) 2008-11-13 US claimed
EP-1794161-A2 MUSCARINIC RECEPTOR ANTAGONISTS Ranbaxy Laboratories Limited (IN) 2007-06-13 EP claimed
WO-2006032994-A2 MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES LIMITED (IN) 2006-03-30 WO claimed
US-20080280883-A1 Muscarinic Receptor Antagonists RANBAXY LABORATORIES LIMITED (IN) 2008-11-13 US disclosed
EP-1794161-A2 MUSCARINIC RECEPTOR ANTAGONISTS Ranbaxy Laboratories Limited (IN) 2007-06-13 EP disclosed
WO-2006032994-A2 MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES LIMITED (IN) 2006-03-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080280883-A1 Muscarinic Receptor Antagonists CHRM3, CHRM5, CHRM2 CHRM3 1/4885MEN1 1629/4885KMT2A 2763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.