Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 14/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 13/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 11/20 | 0.57 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.57 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.57 |
| ▸ | TSPO | P30536 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.57 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.57 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4886957 | 1.00 | CHRM3 (0.60) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL4886984 | 1.00 | CHRM3 (0.60) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Mazaticol SCHEMBL34619 | 0.86 | CHRM3 (0.51) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL14472825 | 0.85 | CHRM3 (0.60) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL16742011 | 0.85 | CHRM3 (0.60) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL1900207 | 0.85 | CHRM3 (0.60) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL14278854 | 0.85 | CHRM3 (0.60) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Mazaticol SCHEMBL182361 | 0.85 | CHRM3 (0.50) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL12152514 | 0.84 | CHRM3 (0.54) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Mazaticol SCHEMBL17747972 | 0.84 | CHRM3 (0.50) | CHRM3CHRM2CHRM1CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080027094-A1 | Tropane Compounds and Pharmaceutical Compositions Comprising the Same as an Active Ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-01-31 | — | — | US | disclosed |
| EP-1785421-A1 | TROPAN COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027094-A1 | Tropane Compounds and Pharmaceutical Compositions Comprising the Same as an Active Ingredient | CHRM1, CHRM3, CHRM2 | CHRM3 2/4885CHRM2 3/4885CHRM1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.