SCHEMBL4887083

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10020269	0.87	GSK3B (0.76)	GSK3BPTPN1NPC1RAB9AHDAC3
	SCHEMBL11974547	0.80	HAO1 (0.64)	GSK3BHAO1PTPN1NPC1RAB9A
	SCHEMBL9378151	0.78	HAO1 (0.52)	GSK3BHAO1PTPN1NPC1RAB9A
	SCHEMBL28443057	0.78	GSK3B (0.64)	GSK3BPTPN1NPC1RAB9AKDM4E
	SCHEMBL11695106	0.78	GSK3B (0.64)	GSK3BPTPN1NPC1RAB9A
	SCHEMBL11826389	0.78	HDAC3 (0.57)	GSK3BHAO1PTPN1NPC1RAB9A
	SCHEMBL8997450	0.76	GSK3B (0.61)	GSK3BNPC1RAB9AKDM4ETDP1
	SCHEMBL3119618	0.76	GSK3B (0.61)	GSK3BNPC1RAB9AHDAC3HDAC4
	SCHEMBL658726	0.76	GSK3B (0.64)	GSK3BNPC1RAB9AKDM4EMAPT
	SCHEMBL8772061	0.76	NPC1 (0.61)	GSK3BPTPN1NPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.