Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | MASP2 | O00187 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10020269 | 0.87 | GSK3B (0.76) | GSK3BCYP3A4MEN1KMT2AMAPT | |
| SCHEMBL9547546 | 0.83 | LMNA (0.47) | GSK3BLMNACYP1A2CYP3A4MAOA | |
| SCHEMBL11365527 | 0.80 | MAPT (0.56) | LMNACYP1A2CYP3A4MAOAMEN1 | |
| SCHEMBL11695106 | 0.78 | GSK3B (0.64) | GSK3BRAB9ANPC1 | |
| SCHEMBL3373429 | 0.78 | LMNA (0.47) | LMNACYP1A2CYP3A4MAOAMEN1 | |
| SCHEMBL3181886 | 0.78 | LMNA (0.47) | LMNACYP1A2CYP3A4MAOAMEN1 | |
| SCHEMBL28443057 | 0.78 | GSK3B (0.64) | GSK3BLMNACYP3A4MAPTKDM4E | |
| SCHEMBL4887083 | 0.76 | GSK3B (0.61) | GSK3BCYP3A4MEN1KMT2AMAPT | |
| SCHEMBL3119618 | 0.76 | GSK3B (0.61) | GSK3BLMNAMEN1KMT2AMAPT | |
| SCHEMBL658726 | 0.76 | GSK3B (0.64) | GSK3BLMNAMAPTKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103508930-B | Two (aminodithioformic acid)-1,3-propylene diester compounds and synthetic method, pharmaceutical composition and purposes | PEKING UNIVERSITY (CN) | 2016-01-27 | — | — | CN | disclosed |
| CN-103508930-A | Bis(aminodithioformate)-1,3-propane diester compound, and synthesis method, pharmaceutical composition and use thereof | UNIV BEIJING | 2014-01-15 | — | — | CN | disclosed |
| EP-0498658-B1 | Composition for inducing humoral anergy to an immunogen | JOLLA PHARMA (US) | 1996-09-04 | — | — | EP | disclosed |
| US-5268454-A | Bonding T-cell epitope to polymer | LA JOLLA PHARMACEUTICAL COMPANY (US) | 1993-12-07 | — | — | US | disclosed |
| WO-1992013558-A1 | A COMPOSITION FOR INDUCING HUMORAL ANERGY | LA JOLLA PHARMACEUTICAL (US) | 1992-08-20 | — | — | WO | disclosed |
| EP-0498658-A2 | Composition for inducing humoral anergy to an immunogen | LA JOLLA PHARMACEUTICAL (US) | 1992-08-12 | — | — | EP | disclosed |