Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MITF | O75030 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4887131 | 1.00 | ALDH1A1 (0.40) | ALDH1A1NPC1KMT2AMITFMEN1 | |
| SCHEMBL4373856 | 0.97 | ALDH1A1 (0.40) | ALDH1A1NPC1KMT2AMITFMEN1 | |
| SCHEMBL4543948 | 0.97 | ALDH1A1 (0.40) | ALDH1A1NPC1KMT2AMITFMEN1 | |
| SCHEMBL4361528 | 0.92 | ALDH1A1 (0.44) | ALDH1A1NPC1KMT2AMITFMEN1 | |
| SCHEMBL4361527 | 0.92 | ALDH1A1 (0.44) | ALDH1A1NPC1KMT2AMITFMEN1 | |
| SCHEMBL4888925 | 0.91 | MAPT (0.37) | ALDH1A1NPC1KMT2AMITFMEN1 | |
| SCHEMBL4362881 | 0.91 | MAPT (0.37) | ALDH1A1NPC1KMT2AMITFMEN1 | |
| SCHEMBL14098429 | 0.90 | MAPT (0.39) | ALDH1A1NPC1KMT2AMITFMEN1 | |
| SCHEMBL4375416 | 0.89 | ALDH1A1 (0.44) | ALDH1A1NPC1KMT2AMITFMEN1 | |
| SCHEMBL4375422 | 0.89 | ALDH1A1 (0.44) | ALDH1A1NPC1KMT2AMITFMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080146562-A1 | HALOGENATED QUINAZOLINYL NITROFURANS AS ANTIBACTERIAL AGENTS | ULYSSES PHARMACEUTICAL PRODUCTS INC., | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146562-A1 | HALOGENATED QUINAZOLINYL NITROFURANS AS ANTIBACTERIAL AGENTS | HRH3, HRH1, NQO2 | ALDH1A1 1414/4885NPC1 484/4885KMT2A 3390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.