Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.64 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.49 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.49 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.49 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 4/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3572485 | 0.93 | PPARG (0.61) | PPARGBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL3574590 | 0.93 | PPARG (0.73) | PPARGBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL4823811 | 0.89 | PPARG (0.68) | PPARGBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL4659809 | 0.86 | PPARG (0.57) | PPARGBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL3569656 | 0.84 | PPARG (0.70) | PPARGBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL3569658 | 0.84 | PPARG (0.70) | PPARGBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL3569503 | 0.82 | PPARG (0.60) | PPARGBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL13316081 | 0.82 | PPARG (0.92) | PPARGBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL13316096 | 0.78 | PPARG (1.00) | PPARGBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL3577620 | 0.76 | PPARG (0.62) | PPARGEPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756036-A4 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2008-04-16 | — | — | EP | disclosed |
| EP-1756036-A1 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005100297-A1 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-10-27 | — | — | WO | disclosed |