Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.73 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.53 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.53 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.53 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.53 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 4/20 | 0.47 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4823811 | 0.96 | PPARG (0.68) | PPARGBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL4889178 | 0.93 | PPARG (0.64) | PPARGBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL3569658 | 0.90 | PPARG (0.70) | PPARGBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL3569656 | 0.90 | PPARG (0.70) | PPARGBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL13316081 | 0.89 | PPARG (0.92) | PPARGBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL13316096 | 0.84 | PPARG (1.00) | PPARGBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL3572485 | 0.83 | PPARG (0.61) | PPARGBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL3577620 | 0.83 | PPARG (0.62) | PPARGEPHX2KDM4E | |
| SCHEMBL3569503 | 0.81 | PPARG (0.60) | PPARGBMPR1BBMPR1ATGFBR1ACVRL1 | |
| Isopropylamine SCHEMBL3580363 | 0.80 | PPARG (0.65) | PPARGADORA3ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745439-B2 | Indene derivatives and process for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-29 | — | — | US | disclosed |
| US-20070225288-A1 | Indene Derivatives and Process for the Preparation Thereof | JEIL PHARM. CO., LTD. (KR) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225288-A1 | Indene Derivatives and Process for the Preparation Thereof | INSR, GPR119, PPARA | PPARG 8/4885BMPR1B 835/4885BMPR1A 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.