Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4891844 | 0.96 | TSHR (0.41) | TSHRALDH1A1ZDHHC20MAPTMEN1 | |
| SCHEMBL4894014 | 0.95 | TSHR (0.40) | TSHRALDH1A1ZDHHC20MAPTMEN1 | |
| SCHEMBL4888227 | 0.92 | ALDH1A1 (0.44) | TSHRALDH1A1HSD17B10 | |
| SCHEMBL4891378 | 0.91 | TSHR (0.46) | TSHRALDH1A1 | |
| SCHEMBL4889694 | 0.87 | ALDH1A1 (0.49) | TSHRALDH1A1THRB | |
| SCHEMBL26675841 | 0.86 | TSHR (0.44) | TSHRALDH1A1ZDHHC20 | |
| SCHEMBL4888281 | 0.85 | ALDH1A1 (0.49) | TSHRALDH1A1 | |
| SCHEMBL22719851 | 0.84 | TSHR (0.42) | TSHRALDH1A1 | |
| SCHEMBL5354606 | 0.82 | TSHR (0.44) | TSHRALDH1A1CYP3A4MAPTHSD17B10 | |
| SCHEMBL4893053 | 0.81 | ALDH1A1 (0.43) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293872-A1 | ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER | HENKEL AG & CO. KGAA (DE) | 2008-11-27 | — | — | US | disclosed |
| US-20080287574-A1 | ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER | HENKEL AG & CO. KGAA (DE) | 2008-11-20 | — | — | US | disclosed |