Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4161374 | 0.82 | CHRM4 (0.44) | ALDH1A1CHRM1CHRM3SMN1; SMN2CHRM5 | |
| SCHEMBL1697177 | 0.82 | CHRM4 (0.44) | ALDH1A1CHRM1CHRM3SMN1; SMN2CHRM5 | |
| SCHEMBL5385059 | 0.81 | CHRM4 (0.43) | ALDH1A1CHRM1CHRM3SMN1; SMN2CHRM5 | |
| SCHEMBL23358779 | 0.80 | CHRM3 (0.41) | ALDH1A1KDM4EHPGDHSD17B10CYP19A1 | |
| SCHEMBL20476348 | 0.79 | KDM4E (0.41) | ALDH1A1KDM4EHPGDHSD17B10CYP19A1 | |
| SCHEMBL2340421 | 0.79 | CHRM3 (0.42) | ALDH1A1KDM4EHPGDHSD17B10CYP19A1 | |
| SCHEMBL1707214 | 0.79 | CHRM3 (0.42) | ALDH1A1KDM4EHPGDHSD17B10CYP19A1 | |
| SCHEMBL5473748 | 0.79 | CHRM3 (0.42) | ALDH1A1KDM4EHPGDHSD17B10CYP19A1 | |
| Bromide SCHEMBL1996228 | 0.78 | CHRM3 (0.43) | ALDH1A1KDM4EHPGDHSD17B10CYP19A1 | |
| Bromide SCHEMBL417945 | 0.78 | CHRM3 (0.43) | ALDH1A1KDM4EHPGDHSD17B10CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080027094-A1 | Tropane Compounds and Pharmaceutical Compositions Comprising the Same as an Active Ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-01-31 | — | — | US | disclosed |
| EP-1785421-A1 | TROPAN COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027094-A1 | Tropane Compounds and Pharmaceutical Compositions Comprising the Same as an Active Ingredient | CHRM1, CHRM3, CHRM2 | ALDH1A1 1749/4885KDM4E 4509/4885HPGD 1304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.