Chlorobenzene

Chlorobenzene

SCHEMBL4890118

Clc1ccccc1.Oc1ccccc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.69
CA12 O43570 2/20 0.69
CA1 P00915 2/20 0.69
CA2 P00918 2/20 0.69
CA3 P07451 2/20 0.69
CA4 P22748 2/20 0.69
CA9 Q16790 2/20 0.69
CA14 Q9ULX7 2/20 0.69
GLA P06280 1/20 0.69
TDP1 Q9NUW8 1/20 0.69
CYP1A2 P05177 1/20 0.48
MMP3 P08254 1/20 0.48
BCL2L1 Q07817 1/20 0.48
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
ORAI1 Q96D31 1/20 0.44
ORAI2 Q96SN7 1/20 0.44
ORAI3 Q9BRQ5 1/20 0.44
TRPV6 Q9H1D0 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Dichlorobenzene SCHEMBL4557393 0.94 CA12 (0.69) TSHRCA12CA1CA2CA3
Parachlorophenol SCHEMBL11593393 0.91 CA12 (0.65) TSHRCA12CA1CA2CA3
Parachlorophenol SCHEMBL8016446 0.91 CA12 (0.65) TSHRCA12CA1CA2CA3
Phenol SCHEMBL5544839 0.84 TSHR (0.85) TSHRCA12CA1CA2CA3
Phenol SCHEMBL936069 0.83
SCHEMBL24715429 0.83 TSHR (1.00) TSHRCYP1A2CES2CES1ORAI1
Chlorobenzene SCHEMBL2044 0.83
Chlorobenzene SCHEMBL1568605 0.83 TSHR (1.00) TSHRCYP1A2CES2CES1ORAI1
Chlorobenzene SCHEMBL2168046 0.83 TSHR (1.00) TSHRCYP1A2CES2CES1ORAI1
Chlorobenzene SCHEMBL1330702 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020019596-A1 PHOSPHAZENE COMPOUND, COMPOSITION COMPRISING PHOSPHAZENE COMPOUND, FLAME RETARDANT COMPRISING SAME, AND USE THEREOF 潍坊医学院 2020-01-30 WO claimed
CN-110316808-A A kind of method and apparatus for handling organic wastewater by catalytic wet air oxidation 北京理工大学 2019-10-11 CN claimed
CN-110204577-A A kind of phosphorus nitrile compounds, the composition including the phosphorus nitrile compounds, the fire retardant comprising it and application 潍坊医学院 2019-09-06 CN claimed
CN-110105201-A A kind of R-(+) -2-(4- hydroxyphenoxy) propionic acid preparation method 苏州开元民生科技股份有限公司 2019-08-09 CN claimed
CN-109358121-A The detection method of polystream phenol in a kind of dyestuff 江苏德旺化工工业有限公司 2019-02-19 CN claimed
CN-109134544-A Phosphazene compound, composition comprising phosphazene compound, flame retardant comprising phosphazene compound and application of phosphazene compound 潍坊医学院 2019-01-04 CN claimed
CN-108689810-A To the synthetic method of methoxy ethyl phenol 连云港市工投集团利海化工有限公司 2018-10-23 CN claimed
CN-108238952-A The synthetic method of organic synthesis intermediate 4- nitro -1,8- naphthalenedicarboxylic acids 成都切斯特科技有限公司 2018-07-03 CN claimed
CN-108239027-A The synthetic method of pharmaceutical intermediate 1- methyl -2- quinolinones 成都卡迪夫科技有限公司 2018-07-03 CN claimed
CN-108238864-A The synthetic method of antiarrhythmic drug intermediate 1- (2,6- dimethoxys) -2- acetone 成都切斯特科技有限公司 2018-07-03 CN claimed
CN-101195711-B Polyamic acid composition and alignment film prepared from same DALI POLYMER CO LTD 2012-07-04 CN claimed
CN-101648978-A Preparation method of high purity hexaphenoxycyclotriphosphazene ZIBO LANYIN CHEMICAL CO LTD 2010-02-17 CN claimed
US-20080226845-A1 Polyamic acid-based composition and liquid crystal orienting film DAILY POLYMER CO., LTD. 2008-09-18 US claimed
CN-101195711-A Polyamic acid composition and alignment film prepared from same DALI POLYMER CO LTD (CN) 2008-06-11 CN claimed
US-20080058496-A1 Polyamic acid-based composition, and liquid crystal orienting agent and orienting film containing the same DAILY POLYMER CO., LTD. 2008-03-06 US claimed
CN-101085867-A Polyamic acid composition, and liquid crystal alignment agent and alignment film using same DAILY POLYMER CORP (CN) 2007-12-12 CN claimed
US-5032481-A Blend of polyester and polycarbonate EASTMAN KODAK COMPANY (US) 1991-07-16 US claimed
EP-0103369-A2 Novel polyesters having p-hydroxybenzoic acid recurring units EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-03-21 EP claimed
US-4140644-A DIMETHYL-1,3-PROPANEDIOL/2,2-/, DIETHYLENE GLYCOL AND TEREPHTHALIC ACID EASTMAN KODAK COMPANY (US) 1979-02-20 US claimed
US-4092364-A Caustic hydrolysis of chlorobenzene to diphenyl oxide THE DOW CHEMICAL COMPANY (US) 1978-05-30 US claimed