SCHEMBL4890422

SCHEMBL4890422

COC(=O)N(C)c1nc2ccccc2[nH]1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.54
TSHR P16473 1/20 0.54
POLB P06746 2/20 0.53
SMN1; SMN2 Q16637 5/20 0.50
KDM4E B2RXH2 5/20 0.50
ALDH1A1 P00352 5/20 0.50
HSD17B10 Q99714 4/20 0.50
MAPT P10636 4/20 0.50
LMNA P02545 6/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C19 P33261 1/20 0.49
RAB9A P51151 5/20 0.48
NPC1 O15118 4/20 0.48
PKM P14618 4/20 0.48
HPGD P15428 2/20 0.48
NFKB1 P19838 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48
BCHE P06276 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27955859 0.84 BCHE (0.48) POLBSMN1; SMN2KDM4EALDH1A1HSD17B10
SCHEMBL27309240 0.84 POLB (0.52) ALOX15TSHRPOLBSMN1; SMN2KDM4E
SCHEMBL251109 0.83 LMNA (0.53) POLBSMN1; SMN2KDM4EALDH1A1HSD17B10
SCHEMBL16446115 0.81 LMNA (0.51) POLBSMN1; SMN2KDM4EALDH1A1HSD17B10
SCHEMBL4888617 0.81 LMNA (0.56) ALOX15POLBSMN1; SMN2KDM4EALDH1A1
SCHEMBL11192326 0.80 LMNA (0.51) ALOX15POLBSMN1; SMN2KDM4EALDH1A1
Zinc Ion SCHEMBL30095327 0.80 LMNA (0.50) POLBSMN1; SMN2KDM4EALDH1A1HSD17B10
SCHEMBL28716345 0.80 POLB (0.38) ALOX15TSHRPOLBSMN1; SMN2KDM4E
SCHEMBL11204833 0.78 POLB (0.47) ALOX15POLBSMN1; SMN2KDM4EALDH1A1
SCHEMBL11599910 0.78 POLB (0.47) TSHRPOLBSMN1; SMN2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113348199-A Branched organosilicon compounds, methods of making branched organosilicon compounds, and copolymers formed therewith 美国陶氏有机硅公司 2021-09-03 CN disclosed
CN-113348174-A Branched organosilicon compounds, methods of making the branched organosilicon compounds, and related compositions 美国陶氏有机硅公司 2021-09-03 CN disclosed
CN-113330055-A Acrylate-functional branched organosilicon compounds, methods of making, and copolymers formed therewith 美国陶氏有机硅公司 2021-08-31 CN disclosed
CN-113330054-A Branched organosilicon compounds, methods of making, and copolymers formed therewith 美国陶氏有机硅公司 2021-08-31 CN disclosed
CN-113195596-A Branched organosilicon compounds, method for producing branched organosilicon compounds, and compositions containing branched organosilicon compounds 美国陶氏有机硅公司 2021-07-30 CN disclosed
CN-113166423-A Branched organosilicon compounds, method for producing branched organosilicon compounds, and compositions containing branched organosilicon compounds 美国陶氏有机硅公司 2021-07-23 CN disclosed
CN-101980865-A Hydrophilic member, fin member, aluminum fin member, heat exchanger and air conditioner FUJIFILM CORP 2011-02-23 CN disclosed
US-20080138385-A1 Antibacterial Composition, Antibacterial Molding, Solution Containing Antibacterial Composition, Detergent, Surface of Tatami Mat and Tatami Mat IDEMITSU TECHNOFINE CO., LTD. (JP) 2008-06-12 US disclosed
EP-1779727-A1 ANTIBACTERIAL COMPOSITION, ANTIBACTERIAL MOLDING, SOLUTION CONTAINING ANTIBACTERIAL COMPOSITION, DETERGENT, SURFACE OF TATAMI MAT AND TATAMI MAT Idemitsu Technofine Co. Ltd (JP) 2007-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080138385-A1 Antibacterial Composition, Antibacterial Molding, Solution Containing Antibacterial Composition, Detergent, Surface of Tatami Mat and Tatami Mat TPMT, KAT5, CARM1 ALOX15 2278/4885TSHR 2435/4885POLB 701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.