SCHEMBL489044

SCHEMBL489044

Nc1ccc(Br)cc1S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29895644 1.00
Fluoride SCHEMBL29290721 0.97 KDM4E (0.43)
SCHEMBL27518808 0.97 KDM4E (0.43)
SCHEMBL5973080 0.97 KDM4E (0.43)
SCHEMBL489124 0.79
SCHEMBL30470728 0.79
Hydrochloric Acid SCHEMBL10986542 0.77 KDM4E (0.39)
Hydrochloric Acid SCHEMBL9674933 0.75 KDM4E (0.38)
SCHEMBL29394596 0.75
SCHEMBL30141068 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798186-A Photosensitizer and preparation method and application thereof 山东大学 2025-04-11 CN claimed
CN-111187233-B Polysubstituted benzothiazole and derivative and synthesis method thereof 湘潭大学 2023-05-30 CN claimed
CN-111187233-A Polysubstituted benzothiazole and derivative and synthesis method thereof 湘潭大学 2020-05-22 CN claimed
CN-102786532-B Sulfur heterocyclic compound and preparation process thereof UNIV BEIJING FORESTRY 2015-06-03 CN claimed
CN-102786532-A Sulfur heterocyclic compound and preparation process thereof UNIV BEIJING FORESTRY 2012-11-21 CN claimed
US-5149755-A Aroatmic amine and halide reactants EASTMAN KODAK COMPANY (US) 1992-09-22 US claimed
CN-119320374-B Method for synthesizing 3-sulfonyl substituted chromone derivative by photocatalysis JIANG University OF TECHNOLOGY (CN) 2026-05-26 CN disclosed
US-12478621-B2 Substituted aminoquinolones as dgkalpha inhibitors for immune activation DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2025-11-25 US disclosed
CN-119798186-A Photosensitizer and preparation method and application thereof 山东大学 2025-04-11 CN disclosed
CN-119564686-A DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) 拜耳公司 2025-03-07 CN disclosed
CN-119523983-A DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) 拜耳公司 2025-02-28 CN disclosed
CN-119424429-A DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) 拜耳公司 2025-02-14 CN disclosed
CN-119320374-A Method for synthesizing 3-sulfonyl substituted chromone derivative by photocatalysis 浙江工业大学 2025-01-17 CN disclosed
EP-1027055-A1 3-CARBOALKOXY-2,3-DIHYDRO-1H-PHENOTHIAZIN-4(10H)-ONE DERIVATIVES HOWARD UNIVERSITY (US) 2000-08-16 EP disclosed
US-5994349-A ANTIEPILEPTIC AGENTS HOWARD UNIVERSITY (US) 1999-11-30 US disclosed
WO-1999021560-A1 3-CARBOALKOXY-2,3-DIHYDRO-1H-PHENOTHIAZIN-4[10H]-ONE DERIVATIVES HOWARD UNIVERSITY (US) 1999-05-06 WO disclosed
EP-0522469-A2 Preparation of poly(benz(ox, imid, thi)azole) polymers EASTMAN KODAK COMPANY (US) 1993-01-13 EP disclosed
US-5149755-A Aroatmic amine and halide reactants EASTMAN KODAK COMPANY (US) 1992-09-22 US disclosed
US-3984405-A PYRIDO(3,2-B)(1,4)OXAZIN-3(4H)-ONES E. R. SQUIBB & SONS, INC. (US) 1976-10-05 US disclosed
US-3962438-A Anti-arthritic 1H-pyrimido-(5,4,3-kl)phenothiazine-1,3(2H)-diones and 1-thiones SMITHKLINE CORPORATION (US) 1976-06-08 US disclosed