SCHEMBL489080

SCHEMBL489080

Nc1cccc(-c2ccccn2)n1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.71
TP53 P04637 4/20 0.71
SMN1; SMN2 Q16637 4/20 0.71
LMNA P02545 3/20 0.71
CCR1 P32246 3/20 0.71
CCR5 P51681 3/20 0.71
CCR8 P51685 3/20 0.71
ALOX15 P16050 3/20 0.71
L3MBTL1 Q9Y468 3/20 0.71
HTT P42858 2/20 0.71
TDP1 Q9NUW8 2/20 0.71
ALPL P05186 1/20 0.71
HSP90AA1 P07900 1/20 0.71
ALPI P09923 1/20 0.71
ALPG P10696 1/20 0.71
MAPK1 P28482 1/20 0.71
CYP1A2 P05177 1/20 0.61
POLB P06746 1/20 0.61
METAP1 P53582 1/20 0.61
BLM P54132 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30215997 1.00 KDM4E (0.71) KDM4ETP53SMN1; SMN2LMNACCR1
Hydrochloric Acid SCHEMBL30439801 0.98 KDM4E (0.68) KDM4ETP53SMN1; SMN2LMNACCR1
SCHEMBL1256208 0.86 KDM4E (0.53) KDM4ETP53SMN1; SMN2LMNACCR1
SCHEMBL21469731 0.84 ASIC3 (0.60) KDM4ETP53SMN1; SMN2LMNACCR1
SCHEMBL7964803 0.84 KDM4E (1.00) KDM4ETP53SMN1; SMN2LMNACCR1
SCHEMBL30172832 0.84 KDM4E (1.00) KDM4ETP53SMN1; SMN2LMNACCR1
Terpyridine SCHEMBL29357603 0.84 KDM4E (1.00) KDM4ETP53SMN1; SMN2LMNACCR1
Terpyridine SCHEMBL57442 0.84 KDM4E (1.00) KDM4ETP53SMN1; SMN2LMNACCR1
SCHEMBL1073895 0.83 ASIC3 (0.68) KDM4ETP53SMN1; SMN2LMNACCR1
SCHEMBL29601960 0.83 ASIC3 (0.68) KDM4ETP53SMN1; SMN2LMNACCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250362307-A1 PHOTOACTIVE ANTIBODY CONJUGATE LIAO JUNG CHI (TW) 2025-11-27 US claimed
WO-2023196986-A1 PHOTOACTIVE ANTIBODY CONJUGATE Syncell (Taiwan) Inc. (TW) 2023-10-12 WO claimed
CN-113604803-B Etching solution for selectively etching tungsten and titanium nitride 湖北兴福电子材料股份有限公司 2023-04-25 CN claimed
CN-113604803-A Etching solution for selectively etching tungsten and titanium nitride 湖北兴福电子材料有限公司 2021-11-05 CN claimed
CN-107501314-B The method of bipyridyliums Mn catalyst catalysis oxidation silane synthesis silanol 陕西师范大学 2019-08-20 CN claimed
CN-1777427-A Aminoheteroaryl compounds as protein kinase inhibitors SUGEN INC (US) 2006-05-24 CN claimed
US-20250362307-A1 PHOTOACTIVE ANTIBODY CONJUGATE LIAO JUNG CHI (TW) 2025-11-27 US disclosed
EP-4473309-A1 PHOTOACTIVE ANTIBODY CONJUGATE Syncell (Taiwan) Inc. (TW) 2024-12-11 EP disclosed
WO-2023196986-A1 PHOTOACTIVE ANTIBODY CONJUGATE Syncell (Taiwan) Inc. (TW) 2023-10-12 WO disclosed
EP-3185330-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2023-08-16 EP disclosed
CN-113604803-B Etching solution for selectively etching tungsten and titanium nitride 湖北兴福电子材料股份有限公司 2023-04-25 CN disclosed
CN-115850538-A Perfluoro ionic polymer with bipyridine side group and synthesis method and application thereof 山东东岳未来氢能材料股份有限公司 2023-03-28 CN disclosed
CN-114437036-A Novel crystal form of 2-aminopyridine derivative and preparation method thereof 正大天晴药业集团股份有限公司 2022-05-06 CN disclosed
EP-1737852-A2 POLYCYCLIC PYRIDINES AS POTASSIUM ION CHANNEL MODULATORS Icagen, Inc. (US) 2007-01-03 EP disclosed
WO-2006135604-A2 INHIBITORS OF CHECKPOINT KINASES MERCK & CO., INC. (US) 2006-12-21 WO disclosed
CN-1777427-A Aminoheteroaryl compounds as protein kinase inhibitors SUGEN INC (US) 2006-05-24 CN disclosed
WO-2005121126-A1 POLYCYCLIC PYRAZINES AS POTASSIUM ION CHANNEL MODULATORS ICAGEN, INC. (US) 2005-12-22 WO disclosed
WO-2005099673-A1 POLYCYLIC THIAZOLES AS POTASSIUM ION CHANNEL MODULATORS ICAGEN, INC. (US) 2005-10-27 WO disclosed
WO-2005099711-A1 POLYCYCLIC PYRIMIDINES AS POTASSIUM ION CHANNEL MODULATORS ICAGEN, INC. (US) 2005-10-27 WO disclosed
WO-2005100349-A2 POLYCYCLIC PYRIDINES AS POTASSIUM ION CHANNEL MODULATORS ICAGEN, INC. (US) 2005-10-27 WO disclosed