⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL75737 | 1.00 | — | — | |
| SCHEMBL31225133 | 1.00 | — | — | |
| SCHEMBL75738 | 1.00 | — | — | |
| SCHEMBL31266879 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL238775 | 0.97 | — | — | |
| Potassium SCHEMBL31266896 | 0.97 | — | — | |
| SCHEMBL5698765 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL902194 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL238776 | 0.97 | — | — | |
| Bromide SCHEMBL489645 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118217955-B | Chiral (lambda) TpPa-1 COF coated capillary and preparation method and application thereof | 兰州大学 | 2024-07-30 | — | — | CN | claimed |
| CN-118217955-A | Chiral (lambda) TpPa-1 COF coated capillary and preparation method and application thereof | 兰州大学 | 2024-06-21 | — | — | CN | claimed |
| CN-114671989-B | Chiral covalent organic framework material, preparation method and application | 山东师范大学 | 2024-05-28 | — | — | CN | claimed |
| CN-115304729-A | High-crystallinity chiral two-dimensional covalent organic framework material and preparation method thereof | 中国科学院化学研究所 | 2022-11-08 | — | — | CN | claimed |
| CN-114671989-A | Chiral covalent organic framework material, preparation method and application | 山东师范大学 | 2022-06-28 | — | — | CN | claimed |
| CN-112979630-A | Trifluoromethanols as Ror gamma t modulators | 詹森药业有限公司 | 2021-06-18 | — | — | CN | claimed |
| EP-3354651-B1 | TRIFLUOROMETHYL ALCOHOLS AS MODULATORS OF ROR-GAMMA-T | JANSSEN PHARMACEUTICA NV (BE) | 2021-01-06 | — | — | EP | claimed |
| CN-108751219-B | Hierarchical porous EU-1 molecular sieve and synthesis method thereof | 中触媒新材料股份有限公司 | 2020-02-14 | — | — | CN | claimed |
| US-10150762-B2 | Trifluoromethyl alcohols as modulators of RORγt | JANSSEN PHARMACEUTICA, NV (BE) | 2018-12-11 | — | — | US | claimed |
| EP-3029026-B1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | DONG A ST CO LTD (KR) | 2018-12-05 | — | — | EP | claimed |
| US-20090275590-A1 | (1-AZINONE)-SUBSTITUTED PYRIDOINDOLES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2009-11-05 | — | — | US | claimed |
| US-20090227593-A1 | CYCLOBUTYL AMINE DERIVATIVES | ABBOTT LABORATORIES (US) | 2009-09-10 | — | — | US | claimed |
| US-7553964-B2 | Cyclobutyl amine derivatives | ABBOTT LABORATORIES (US) | 2009-06-30 | — | — | US | claimed |
| EP-2049472-A2 | CYCLOPROPYL AMINE DERIVATIVES AS HISTAMIN H3 RECEPTOR MODULATORS | Abbott Laboratories (US) | 2009-04-22 | — | — | EP | claimed |
| US-20080242653-A1 | Cyclopropyl amine derivatives | ABBVIE INC. | 2008-10-02 | — | — | US | claimed |
| EP-1622620-B1 | QUINAZOLINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2008-02-20 | — | — | EP | claimed |
| US-20080021081-A1 | e.g. 4'-2-{[(2S)-2-methylpyrrolidin-1-yl]methyl}cyclopropyl)-1,1'-biphenyl-4-carbonitrile; histamine-3 receptor ligand; neuroleptic agent, neurodegenerative diseases, cognition activator; attention-deficit hyperactivity disorder, schizophrenia, Alzheimer's disease, epilepsy, seizures, allergic rhinitis | ABBVIE INC. | 2008-01-24 | — | — | US | claimed |
| WO-2007150010-A2 | CYCLOPROPYL AMINE DERIVATIVES AS HISTAMIN H3 RECEPTOR MODULATORS | ABBOTT LABORATORIES (US) | 2007-12-27 | — | — | WO | claimed |
| US-20070078133-A1 | Cyclobutyl amine derivatives | ABBVIE INC. | 2007-04-05 | — | — | US | claimed |
| US-20060211714-A1 | Quinazoline derivatives and their use in the treatment of cancer | ASTRAZENECA AB (SE) | 2006-09-21 | — | — | US | claimed |